ID A0A2Y9JLE5_ENHLU Unreviewed; 98 AA.
AC A0A2Y9JLE5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=C-X-C motif chemokine {ECO:0000256|RuleBase:RU361149};
GN Name=LOC111149252 {ECO:0000313|RefSeq:XP_022361918.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022361918.1};
RN [1] {ECO:0000313|RefSeq:XP_022361918.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022361918.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU361149}.
CC -!- SIMILARITY: Belongs to the intercrine alpha (chemokine CxC) family.
CC {ECO:0000256|ARBA:ARBA00010665, ECO:0000256|RuleBase:RU361149}.
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DR RefSeq; XP_022361918.1; XM_022506210.1.
DR AlphaFoldDB; A0A2Y9JLE5; -.
DR STRING; 391180.A0A2Y9JLE5; -.
DR KEGG; elk:111149252; -.
DR OrthoDB; 4264143at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-UniRule.
DR GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00273; Chemokine_CXC; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR001089; Chemokine_CXC.
DR InterPro; IPR018048; Chemokine_CXC_CS.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR033899; CXC_Chemokine_domain.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF202; C-X-C MOTIF CHEMOKINE 10; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR PRINTS; PR00436; INTERLEUKIN8.
DR PRINTS; PR00437; SMALLCYTKCXC.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
DR PROSITE; PS00471; SMALL_CYTOKINES_CXC; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500, ECO:0000256|RuleBase:RU361149};
KW Citrullination {ECO:0000256|ARBA:ARBA00022934};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU361149};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Secreted {ECO:0000256|RuleBase:RU361149};
KW Signal {ECO:0000256|RuleBase:RU361149}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361149"
FT CHAIN 22..98
FT /note="C-X-C motif chemokine"
FT /evidence="ECO:0000256|RuleBase:RU361149"
FT /id="PRO_5015797205"
FT DOMAIN 27..89
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
SQ SEQUENCE 98 AA; 10816 MW; 7B877FE694BB7147 CRC64;
MNRSAVLIFC LIFLTLNGTQ GIPFSRTTRC TCIKISDGSI NPRSLEKLEV IPASQSCPRV
EIIATLKKNG EKRCLNPASK KIKILLKAIS KERSKTSP
//
