ID A0A2Y9JNT4_ENHLU Unreviewed; 193 AA.
AC A0A2Y9JNT4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=P53 apoptosis effector related to PMP-22 {ECO:0000313|RefSeq:XP_022359470.1};
GN Name=LOC111147607 {ECO:0000313|RefSeq:XP_022359470.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022359470.1};
RN [1] {ECO:0000313|RefSeq:XP_022359470.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022359470.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM47 family.
CC {ECO:0000256|ARBA:ARBA00008691}.
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DR RefSeq; XP_022359470.1; XM_022503762.1.
DR AlphaFoldDB; A0A2Y9JNT4; -.
DR STRING; 391180.A0A2Y9JNT4; -.
DR KEGG; elk:111147607; -.
DR OrthoDB; 4571618at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR015664; P53_induced.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR PANTHER; PTHR14399:SF4; P53 APOPTOSIS EFFECTOR RELATED TO PMP-22; 1.
DR PANTHER; PTHR14399; P53-INDUCED PROTEIN RELATED; 1.
DR Pfam; PF00822; PMP22_Claudin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 193 AA; 21496 MW; 182DA60E82E9C1C0 CRC64;
MLRCGLACER CRWILPLLLL SAIAFDIIAL AGRGWLQSSD HVQTSSLWWR CFHEGGGSGS
YDDGCQSLME YAWGRAAAAM LFCGFIILVI CFILSFFALC GPQMLVFLRV IGGLLALAAV
FQIISLVIYP VKYTQTFNLH ANPGVTYIYN WAYGFGWAAT IILIGCAFFF CCLPNYEDDL
LGNAKPRYFY TSA
//
