ID A0A2Y9JP06_ENHLU Unreviewed; 184 AA.
AC A0A2Y9JP06;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ADP-ribosylation factor-like protein 2 {ECO:0000256|ARBA:ARBA00026198};
GN Name=LOC111149831 {ECO:0000313|RefSeq:XP_022362833.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022362833.1};
RN [1] {ECO:0000313|RefSeq:XP_022362833.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022362833.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290, ECO:0000256|RuleBase:RU003925}.
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DR RefSeq; XP_022362833.1; XM_022507125.1.
DR AlphaFoldDB; A0A2Y9JP06; -.
DR STRING; 391180.A0A2Y9JP06; -.
DR KEGG; elk:111149831; -.
DR OrthoDB; 5349301at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04154; Arl2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045873; Arl2.
DR InterPro; IPR044612; ARL2/3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45697:SF2; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR45697; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
SQ SEQUENCE 184 AA; 20889 MW; E4E59EAB55C5AAA2 CRC64;
MGLLTILKKM KQKERELRLL MLGLDNAGKT TILKKFNGED IDTISPTLGF NIKTLEHRGF
KLNIWDVGGQ KSLRSYWRNY FESTDGLIWV VDSADRQRMQ DCRRELQSLL VEERLAGATL
LIFANKQDLP GALSSNAIRE ALELDSIHSH HWCIRGCSAV TGENLLLGVD WLLDDISSRI
FTAD
//
