ID A0A2Y9JQK8_ENHLU Unreviewed; 780 AA.
AC A0A2Y9JQK8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN Name=LOC111148028 {ECO:0000313|RefSeq:XP_022360090.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022360090.1};
RN [1] {ECO:0000313|RefSeq:XP_022360090.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022360090.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022360090.1; XM_022504382.1.
DR AlphaFoldDB; A0A2Y9JQK8; -.
DR STRING; 391180.A0A2Y9JQK8; -.
DR KEGG; elk:111148028; -.
DR OrthoDB; 2882462at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR040024; PPP1R21.
DR InterPro; IPR049372; PPP1R21_C.
DR InterPro; IPR019343; PPP1R21_N.
DR InterPro; IPR019348; PPP1R21_six_helix.
DR PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR Pfam; PF10205; KLRAQ; 1.
DR Pfam; PF21636; PPP1R21_C; 1.
DR Pfam; PF10212; PPP1R21_helical; 1.
DR SMART; SM01254; KLRAQ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT DOMAIN 11..112
FT /note="Protein phosphatase 1 regulatory subunit 21 N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM01254"
FT REGION 84..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 137..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 558..592
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 696..730
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 780 AA; 88296 MW; 3F2708E287F02AF2 CRC64;
MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD
SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKSVFDE DLQKKIEENE
RLHIQFFEAD EQHKHVEAEL RSRLATLEME AAQHQAVVDG LTRKYMETIE KLQNDKAKLE
VKSQTLEKEA KECRLRTEEC QLQLKNLHDD LSGRLEESLS IISEKVPFND TKYSQYNALN
VPLHNRRHQL KMRDIVGQAL AFVQDLVTAL LNFHTYTEQR IQIFPIDSAI EPISPLNQKF
SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLKKILPYQ
LKSLEEECES SLCTSALRAR NLELSQDMKK MTAVFEKLQT YIHLLALPST EPDGLLRTNY
GSVLTNVGAA LHGFHDVVKD ISKHYSQKAT IEHELPTATQ KLITTNDCIL SSLVALTNGA
GKITSFFSNN VDCFIASLSY GPKAASGFIS PLSAECMLQY KRKAAAYMKA LRKPLLESVP
YEEALANRRV LLSSTESREG LAQQVQQSLE KISKLEQEKE HWMLEAQLAK IKLEKENQRI
ADKLRSTSSG QGLGLAQENA TGVNAAGRED VSAKAMLDPA HSTSLIGILT RTSDNEVPDV
ESREDLIKNH YMARIVELTS QLQLADSKSV HFYAECRALS KRLALAEKSK DALTEEMKVA
GQNISRLQDE LTTTKRSYED QLSMMSDHLC SMNETLSKQR EEIDTLKMSS KGNSKKNKSR
//
