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Database: UniProt
Entry: A0A2Y9JX60_ENHLU
LinkDB: A0A2Y9JX60_ENHLU
Original site: A0A2Y9JX60_ENHLU 
ID   A0A2Y9JX60_ENHLU        Unreviewed;      3110 AA.
AC   A0A2Y9JX60;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=centromere protein F {ECO:0000313|RefSeq:XP_022364119.1};
GN   Name=LOC111150802 {ECO:0000313|RefSeq:XP_022364119.1};
OS   Enhydra lutris kenyoni.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Lutrinae;
OC   Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022364119.1};
RN   [1] {ECO:0000313|RefSeq:XP_022364119.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022364119.1};
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
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DR   RefSeq; XP_022364119.1; XM_022508411.1.
DR   KEGG; elk:111150802; -.
DR   Proteomes; UP000248482; Genome assembly.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1890..2032
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2128..2267
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2310..2448
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2966..3009
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          245..264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          513..533
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1717..1736
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2901..3110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..138
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..342
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          350..377
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..459
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          467..487
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          651..713
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          718..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          838..865
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          902..946
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          954..991
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1028..1083
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1117..1151
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1291..1318
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1330..1357
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1395..1415
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1547..1610
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1787..1814
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1822..1856
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1887..1907
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1936..1994
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1999..2082
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2104..2124
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2139..2201
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2209..2275
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2293..2313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2321..2348
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2356..2492
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2500..2600
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2615..2713
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2715..2822
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2830..2860
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2868..2888
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        246..264
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..533
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2901..2928
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2951..2980
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2995..3009
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3020..3074
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3110 AA;  356979 MW;  B4FF30D8A986194C CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQAAEVSLH PSTTPQKIFA TPLTPSQYYT GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKTSQAIPQN TMNHRDIARH QASSSVFSWQ QEKTPTRLSS NALKTPIRRE
     FSASHFSGEQ EVTPSRSTLQ TGKRDANGSF CDNSSNSHLL DQLKAQNQDL RNKISELELH
     LQGQEKEMKG QANKCQELQL QLEKAKAELV EKEKILNKNR DELVRSTAQY DQASTKCTTL
     EQKLKRLSED LSCQRQNAES ARCSLEQKLK EKEKEFQEEL CRQQRAFQAL DQECVQMKAR
     LTQELQQAKN TRNILQADLD KVTSGKHQLE KTLEEFKQKF CRTEQALQAS QVQENELRRS
     SEEVKKEFSV LKSQSEQRAR EVCHLEEELR KARQSLSQSQ NATEEMRAKN ASQETMLRDL
     QEKINQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNDKLSK IEKESEALLL
     ALELKKKDCE ELKEEKALFA RWKSENEQLL SQLESEKGSL QSKINHLETC LKTQQIRSHE
     YNEKVRTLEM ESENLSVEIR NLHNVIDSKT VEVERQKQAY ADLQQKAEFS DQKHKKEVEN
     MCLKISELTG QVDDLEHKLQ LLSSEVIDKD QRYQDSQAEY ENLQDLVKSK DSSLVTNEAL
     NRSLLAFEQQ PAMNNSFAIT GEQGSMPSER STCHLEADPS PKNSAILQNR VVSLEFSLES
     QKQMNSDLQK QCEELVQIRG EIEENLIKAE QMHQSFVAET SQRISKLQED TSVHQNAFTE
     TLAALENKER EFQLLNEKLE TEQAEIQELK KSNHLLQDSL KELQLLSEAL SLEKKEMSST
     ISLNRKEIED LTQENATLKE INATLNQEKI NLLQKSESFV NCIDERDKSI SELSNQHKQE
     RLILQQRCEE TGHALEDLSE KYSAAQEKNS QLECLLNECT IACENRQKEL EHLKETFARE
     QQDFVTKLAL AEETNQNLVL ELGAVRHDLS SEIADIQNNS KSEADGLKQE IMTLKEEQSK
     MQKELNALLQ ENEHLVTLMK TKQEHQILES EPVSDAVEGV SEINKCHIQL PMDLEVKDPS
     LDCHNAQLVQ LEAKRIRELK LQESEKGKEC PLHELCTIRM ELETGNLQPE AQSPEPSGPK
     DCDVGTEEKY MSVLHELSAS QNDHAHLLCS LQTAMSKLSE LEKMCEMLQV EKLELMSELN
     DSRSECITAT NKMAEEMEKL VNEVKILNNE NGLLQGELVK EMAEGESCER QNEQKRASLN
     PLGDSNCYEH LTLSNKEVQM HFAELQEKFS SLQSEHKILH DQHRQVSSKM SELQSYVDTL
     KAENSILSTS LRSFQGDLVK EEMPGPEEGH FLSLSFSCVT DSPGLTRLGE SSFCKDILDQ
     TGETSLLNNL DGTISANQSN VEERSCCSLE EENLTKKEIL SAPARSVEEL ETLCQMYMQS
     LKELEEKIES QEIMKNKEIK ELEQILSSER EELDCLRKQY LSENEQWQQK LTSVTMEMES
     KLAAEKKQTE HLSFELEVAR LQLQGLDLSS RSLLGTDIED VLRGGNNSCD VKESEEYTLE
     TQERTPKRDI HQICEEGIQQ DLSREMEKIT KTSPVRFTGE EWSREQSPET PAEDKTQGYL
     ECISQLSLSG PNAPVPVDFL ETQVTIQNLQ LQVKESSNEN LRLLHVIEER DKKVESLLNE
     IKELDSKLDL QEAQITTKTE ACVELEKIVG KLKKEKSNLR ERLESFACDN QELHQRTESL
     EGLNSNLETG TDKRSHAVIE ENMAEVNDNW RERFLDVEKE LKRIQSEKGS IEHHALSVEA
     DLETVQTEKL YLEKDNESKQ KLITCLEEEL SVVTNERNQL HGELDTLSKE NKELDLMSEK
     MKEKIHELES HQDECLHHID VAEAELKDKA QLIQTLSSNV TELSEENTRL QEQLQSLEKD
     SQALSLVKSE LEIQIEQLNK EKESLAGESE SLQTRLHESE HEKLTIAKAL EDALMEKGEV
     AVRLSSTQEE VHQLRKGIEK LRVRIEADDK KQLHVLEKLR VSERKNDSLQ DKVENLEREL
     QMSEENQELV ILDAENSKAE VEALKTQMEL MTKTLKDLEL DLGTVKFEKE NLIKQLQEKQ
     GQVSELDTLL SSLKSRLEEE EKEKIETREE SKAALEMLQT QLKELNEEVI ALCHDQEIQK
     VEEQSMDISG QKIHQLRNSI EKLKVRLEAD EKEQLQVLRK LKESEHHADL LKDRVENLER
     ELEISGKNQE CMILEAENSK AEVGTLKAKI EEMAQNLRDL ELDLVHIRSE KENVIEELQK
     AQGRVSELEI LKSSFENLLQ EKEQEKIQMR EDSKIAVEML QTQVKELNQK AEALCHDQEA
     WKAQAQNLHS QVDALELEKT QLLQDLDEVK NNYLNVQSSA NGLLQQVEDG KHKLEKKEEE
     ISLLKNQIQD REQLTSKLAQ VEGEQQLWKK QKGELENLLV ELEQKSQVLQ AKNDTLQDTL
     EALQRSHKDL EKELELRKME NVSFVEKVNA MTGKETELQR EMHEMVQKTT ELKEEFTRER
     NRLTEELNIM SEDIKSSKGQ LKELMLENSE LKKSLDCIHK DQMEKEEKVR EEIAEYQLQL
     QEAEKKHQAL LLDTNKQYEM EIQTYREKLS SQEECLSSQK AEVDLLKSSK EELNNSLKAT
     TQILEELKKT QADNVKYANQ LKKENERAQG KIKLLIKSCK QLEEEKEMLQ KELSKIEAAQ
     EKQKTGTAVD SNVEELMAEI KELKETLEEK NKEADEYLDK YCSLLISHEK LEKAKEMLET
     QVARLSSQSK LNLQNSPLLN SVVSEDSPAP SATEKKLSSS QNKTSGKRQR STGIREDGGG
     TAPSTPETFS KKSRKAVKSG IHPTEDTRDT EFEPEGLPEV VKKGFADIPT GKTSPYVLRR
     TTMPTRTSPR LAAQKLAPSP LSLNKENQAE TSQPTAGGSR SQKVKVAQQS PVDSSAPFRE
     PTTRSLSVSN LPDRSPADSP REGLRAKRGR LAPSPEAVPD SKSSENCRVQ
//
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