ID A0A2Y9JXN4_ENHLU Unreviewed; 334 AA.
AC A0A2Y9JXN4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DNA repair protein RAD51 homolog 4 isoform X2 {ECO:0000313|RefSeq:XP_022365611.1};
GN Name=LOC111151735 {ECO:0000313|RefSeq:XP_022365611.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022365611.1};
RN [1] {ECO:0000313|RefSeq:XP_022365611.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022365611.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022365611.1; XM_022509903.1.
DR AlphaFoldDB; A0A2Y9JXN4; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd19489; Rad51D; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047323; Rad51D_C.
DR InterPro; IPR048943; RAD51D_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR46457; DNA REPAIR PROTEIN RAD51 HOMOLOG 4; 1.
DR PANTHER; PTHR46457:SF1; DNA REPAIR PROTEIN RAD51 HOMOLOG 4; 1.
DR Pfam; PF08423; Rad51; 1.
DR Pfam; PF21794; RAD51D_N; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00023204};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT DOMAIN 96..237
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
SQ SEQUENCE 334 AA; 35299 MW; 196D406CDF950CC2 CRC64;
MPPGQASPSA APPGPPGNMG VLRAGLCPGL TQDTVGQLRT RGIRTVVDLV SADLEDVAQK
CALSYKALVA LRRVLLAQFS AFPCNGADLY EELKTSTAIL STGIQSLDKL LDAGLYTGEV
TEIVGGPGSG KTQVCLRVAA NVAYSLQQNV LYIDSNGGLT ASRILQLLQA RTPDEEQQVS
SASATVKVVV VDSVTAVVSP LLGGQQREGL ALMMQLAREL KTLARDLGVA VMVTNHMTRD
RDSGDLKPAL GRSWSFVPST RILLDIEEGA GASGSWRRAR LTKSPRLPTG FQEVVDIGTW
GPPEQSPASQ GRSDRTVLLI GKSRGHQAPH LCAR
//
