ID A0A2Y9JZF9_ENHLU Unreviewed; 417 AA.
AC A0A2Y9JZF9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Advanced glycosylation end product-specific receptor isoform X2 {ECO:0000313|RefSeq:XP_022366256.1};
GN Name=LOC111152179 {ECO:0000313|RefSeq:XP_022366256.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022366256.1};
RN [1] {ECO:0000313|RefSeq:XP_022366256.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022366256.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022366256.1; XM_022510548.1.
DR AlphaFoldDB; A0A2Y9JZF9; -.
DR STRING; 391180.A0A2Y9JZF9; -.
DR OrthoDB; 4637563at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11973:SF20; ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTOR; 1.
DR PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_022366256.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..417
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016062623"
FT TRANSMEM 354..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..115
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 128..235
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 249..330
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 381..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 417 AA; 44402 MW; 019F3F63A14068C6 CRC64;
MAAGAAAGAW VLVLSLWGAV VGDRNITARI GKPLVLNCRG APKKPPQQLE WKLNTGRTEA
WKVLSPEGGS WDSVAQVLPN GSLLLPAVGI QDEGTFRCQA TSRNGKEMRS AYQVQVYQIP
GKPEIVSPAS ELMPGVPNKV VEAGGSRKQS LFPQVGTCVS EGGYPAGTLN WHSEGKLLIP
DGKGVSVLEE TTRHPQTGLF TLQSALMVTP AWGGAPHLTF SCSFSPGLPR RRALHTASIQ
LRVWEPVPPE VRVMVQPEGG KLVRGGTVTL TCETPAQSSL QIHWIKDGIP LHLAPSPVLL
LNDVEFDDEG SYSCVATYPG HGPQESPAVR VVIAQPGTEE PIAGSVEGQG LGTVALALGI
LGGLGIAALL IGAIMWRRQR RRREERKAPE NQEEEEERAE LNQSEEPEPA ESGAAGP
//
