ID A0A2Y9K2D9_ENHLU Unreviewed; 303 AA.
AC A0A2Y9K2D9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=RING finger protein 148 isoform X1 {ECO:0000313|RefSeq:XP_022365859.1};
GN Name=LOC111151931 {ECO:0000313|RefSeq:XP_022365859.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022365859.1};
RN [1] {ECO:0000313|RefSeq:XP_022365859.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022365859.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022365859.1; XM_022510151.1.
DR AlphaFoldDB; A0A2Y9K2D9; -.
DR KEGG; elk:111151931; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02122; PA_GRAIL_like; 1.
DR CDD; cd16802; RING-H2_RNF128-like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22765; RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22765:SF53; RING FINGER PROTEIN 148; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..303
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015943267"
FT TRANSMEM 190..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 256..297
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 303 AA; 33936 MW; 90CC5AE5FEF93FB6 CRC64;
MSLLRITPST HSSVSSQLLR LSVFLLLSLP ASKGKAIWTA HLNITFQVGN RIISELGESG
VFGNHSPLER VSGAVVLPEG WNQNACNPMT NFSRPEQADS WLALIERGGC TFTHKINVAA
EKGANGVIIY NYPGTGNKVF PMSHQGTENI VAVMIGNLKG MELLHLIQKG VYVTIIIEVG
RMHMPWLSHY IMSLFTFLAA TVAYLFLYCA WRPRVPNSST RRRRQIKADV KKAIGQLQLR
VLKEGDKELD PDEDSCVVCF DIYKPQDVVR ILTCKHFFHK ACIDPWLLAH RTCPMCKCDI
LKT
//
