ID A0A2Y9K9D2_ENHLU Unreviewed; 475 AA.
AC A0A2Y9K9D2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger protein 622 {ECO:0000313|RefSeq:XP_022368204.1};
GN Name=LOC111153472 {ECO:0000313|RefSeq:XP_022368204.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022368204.1};
RN [1] {ECO:0000313|RefSeq:XP_022368204.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022368204.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the REI1 family.
CC {ECO:0000256|ARBA:ARBA00034126}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022368204.1; XM_022512496.1.
DR AlphaFoldDB; A0A2Y9K9D2; -.
DR STRING; 391180.A0A2Y9K9D2; -.
DR KEGG; elk:111153472; -.
DR OrthoDB; 180831at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR041661; ZN622/Rei1/Reh1_Znf-C2H2.
DR InterPro; IPR040025; Znf622/Rei1/Reh1.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR13182; ZINC FINGER PROTEIN 622; 1.
DR PANTHER; PTHR13182:SF8; ZINC FINGER PROTEIN 622; 1.
DR Pfam; PF12756; zf-C2H2_2; 1.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SMART; SM00451; ZnF_U1; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 6..28
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 69..91
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 136..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 53983 MW; 3AB751D42682BF52 CRC64;
MATYTCITCR VAFGDADVQR AHYKTDWHRY NLKRKVADMA PVTAEGFQER VRAQRAVTEQ
ESKGTATYCT VCSKKFASFN AYENHLKSRR HVELEKKAVR AVSRKVEMMN EKNLEKGLGV
DSVDKDAMNA AIQQAIKAQP SLSPKKAPAA PEESPPRSPA SLARAGRAAH ERDPAEKPPR
LQWFEQQAKK FTKQQQEEES EEDLDEEDWE DIDSEEELEY EDADATDEAE EPDAEGEEAG
RGPFVGAIPI TDCLFCPHHS SSLVKNVAHM TKVHSFFIPD IEYLSDLKGL IRYLGEKVGV
GKICLWCNEK GKSFYSTEAV QAHMNDKSHC KLFADGDAAL EFADFYDFRS SYPDYKEGEY
PDETELCSER LLGYDDETME LILPSGARLG HRSLMRYYKQ RFGLSRAVAV AKNRKAVGRI
LQQYRALGWT GSTGAALVHE RDMQYVQRMK SKWLLKTGMK NNATKQMHFR PQVRF
//
