ID   A0A2Y9KA54_ENHLU        Unreviewed;       710 AA.
AC   A0A2Y9KA54;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=F-box only protein 40 {ECO:0000313|RefSeq:XP_022370607.1};
GN   Name=LOC111154939 {ECO:0000313|RefSeq:XP_022370607.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022370607.1};
RN   [1] {ECO:0000313|RefSeq:XP_022370607.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022370607.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022370607.1; XM_022514899.1.
DR   AlphaFoldDB; A0A2Y9KA54; -.
DR   STRING; 391180.A0A2Y9KA54; -.
DR   KEGG; elk:111154939; -.
DR   OrthoDB; 5397239at2759; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd22175; F-box_FBXO40; 1.
DR   Gene3D; 3.30.40.150; TRAF-like zinc-finger, N-terminal subdomain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR031890; Fbxo30/Fbxo40.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001293; Znf_TRAF.
DR   InterPro; IPR043013; Znf_TRAF_N.
DR   PANTHER; PTHR15933:SF1; F-BOX ONLY PROTEIN 40; 1.
DR   PANTHER; PTHR15933; PROTEIN CBG16327; 1.
DR   Pfam; PF15966; F-box_4; 1.
DR   Pfam; PF15965; zf-TRAF_2; 1.
DR   SUPFAM; SSF81383; F-box domain; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 1.
DR   PROSITE; PS50181; FBOX; 1.
DR   PROSITE; PS50145; ZF_TRAF; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}.
FT   DOMAIN          54..96
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50145"
FT   DOMAIN          571..625
FT                   /note="F-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50181"
FT   ZN_FING         54..96
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
SQ   SEQUENCE   710 AA;  80088 MW;  3CF5B618CF8AF04D CRC64;
     MGRARRPLPG QHRHCEKCFN RHCHIPVEPD VSCLVINCHL SCGATFHMCK EAEHELLCPL
     EEVPCLNSEY GCPLSMSRHK LAKHLQVCPA SVVCCSMEWN RWPNVDSETT LHENIMKETP
     SEECLDTALA LQDQKVLFRS LKMVELFPET REPTEEEPTM NGEASWEEMG GAVGGAEASL
     VPHGALSATN GEMVELSQEE REVLAKTKEG MDLAKFDKWE NIFSKEHAAS ALTTSSVGCE
     SKSGYNPGKE QFSSDNNMVG EETLKEKEPQ EKQKQQDFHA ALETTGLAPW QDGVLERLKT
     AVDAKDYNMY LVHNGRMLIH FGQMPACTPK ERDFVYGNLE AQDVKTVYTF KVPVSYCGKR
     ARVGDAMSSS KPSEHKAVDT SDLGITVEDL PKSDLIKTTL LCALERELKG HVISESRSID
     GLFMDFATQT YNFKPEQFSS GTVLADLLTN ANPGGLHVEL HSECVTRRHN KSSSAFTFTC
     NKFFRRDEFP LHFKNVHTDI QSCLNGWFQH RCPLAYLGCT FIQNHFRPPG QKAKVIYSQE
     LKTFAIKPEV ASELSERKKN NHLSGHGGKS QNCLTSLPLE VLQYIAGFLD SISLSQLSQV
     SVLMRNICAT LLQERGMVLL QWKKKRYSQG GTSWRVHREI WQFSSLFSKI KSWEFNEVAS
     MAEHLKDCPF NIVEHKTDPI LLTSMCQLQE QARESLVTTF RARPRGRHTC
//