ID   A0A2Y9KBI5_ENHLU        Unreviewed;       645 AA.
AC   A0A2Y9KBI5;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Kelch-like protein 17 isoform X4 {ECO:0000313|RefSeq:XP_022370488.1};
GN   Name=LOC111154848 {ECO:0000313|RefSeq:XP_022370488.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022370488.1};
RN   [1] {ECO:0000313|RefSeq:XP_022370488.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022370488.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022370488.1; XM_022514780.1.
DR   AlphaFoldDB; A0A2Y9KBI5; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd18456; BACK_KLHL17; 1.
DR   CDD; cd18246; BTB_POZ_KLHL17_actinfilin; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR   PANTHER; PTHR45632; LD33804P; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   PRINTS; PR00501; KELCHREPEAT.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          95..162
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..42
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  70275 MW;  2F89CF5DA0D723AC CRC64;
     MQPRGERPAG RTQSPEHGSP GPGPEAPPPP PPPQPQPPAP EAERARPRQA RPTAPMEGAM
     QLLSREGHTV SHNSKRHYHD AFVAMSRMRQ RGLLCDIVLH VAAKEIRAHK VVLASCSPYF
     HAMFTNEMSE SRQTHVTLHD IDPQALDQLV QFAYTAEIVV GEGNVQTLLP AASLLQLNGV
     RDACCKFLLS QLDPSNCLGI RGFADTHSCS DLLKAAHRYV LQHFVDVAKT EEFMLLPLKQ
     VLELVSSDSL NVPSEEDVYR AVLSWVKHDV DARRQHVPRL MKCVRLPLLS RDFLLGHVDA
     ESLVRHHPDC KDLLIEALKF HLLPEQRGVL GTSRTRPRRC EGAGPVLFAV GGGSLFAIHG
     DCEAYDTRTD RWHVVASMST RRARVGVSAV GNRLYAVGGY DGTSDLATVE SYDPVTNTWQ
     PEVSMGTRRS CLGVAALHGL LYAAGGYDGA SCLNSAERYD PLTGTWTSIA AMSTRRRYVR
     VAMLDGNLYA VGGYDSSSHL ATVEKYEPQV NAWTPVASML SRRSSAGVAV LEGALYVAGG
     NDGTSCLNSV ERYSPKAGAW ESVAPMNIRR STHDLVAMDG WLYAVGGNDG SSSLNSIEKY
     NPRTNKWVAA SCMFTRRSSV GVAVLELLNF PPPSSPTLSV SSTSL
//