ID   A0A2Y9KDY1_ENHLU        Unreviewed;       248 AA.
AC   A0A2Y9KDY1;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Tropomyosin alpha-1 chain {ECO:0000256|ARBA:ARBA00041188};
DE   AltName: Full=Alpha-tropomyosin {ECO:0000256|ARBA:ARBA00042447};
DE   AltName: Full=Tropomyosin-1 {ECO:0000256|ARBA:ARBA00042056};
GN   Name=LOC111153107 {ECO:0000313|RefSeq:XP_022367615.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022367615.1};
RN   [1] {ECO:0000313|RefSeq:XP_022367615.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022367615.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the tropomyosin family.
CC       {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR   RefSeq; XP_022367615.1; XM_022511907.1.
DR   AlphaFoldDB; A0A2Y9KDY1; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 2.
DR   InterPro; IPR000533; Tropomyosin.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   PANTHER; PTHR19269:SF80; TROPOMYOSIN ALPHA-1 CHAIN; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT   REGION          81..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  28612 MW;  AD9BE1EBDFBFA3B1 CRC64;
     MAGSSSLEAV RRKIRSLQEQ ADAAEERAGS LQRELDYERK LRETAEADVA SLNRRIQLVE
     EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE
     DADRKYEEVA RKLVIIESDL ERAEERAELS ESKCAELEEE LKTVTNNLKS LEAQAEKYSQ
     KEDKYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EDELYAQKLK YKAISEELDH
     ALNDMTSM
//