ID   A0A2Y9KE76_ENHLU        Unreviewed;       324 AA.
AC   A0A2Y9KE76;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE            EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN   Name=LOC111155904 {ECO:0000313|RefSeq:XP_022372077.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022372077.1};
RN   [1] {ECO:0000313|RefSeq:XP_022372077.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022372077.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC       {ECO:0000256|ARBA:ARBA00005771, ECO:0000256|RuleBase:RU361155}.
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DR   RefSeq; XP_022372077.1; XM_022516369.1.
DR   AlphaFoldDB; A0A2Y9KE76; -.
DR   STRING; 391180.A0A2Y9KE76; -.
DR   KEGG; elk:111155904; -.
DR   OrthoDB; 3083090at2759; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR11783:SF329; SULFOTRANSFERASE 1C3; 1.
DR   PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU361155}.
FT   DOMAIN          66..316
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00685"
SQ   SEQUENCE   324 AA;  38042 MW;  B75AA79D714CBCFE CRC64;
     MKTESAGQTQ SQLVPRASVK MSLDEMKDHQ LVGKYIQPET REVDGVLMTK IISDNWDKIW
     NFQAKPDDLL IASYAKSGTT WTQEIVDMIQ NDGDVQKCQR ANTFDRHPFI EWTFPPPLNS
     GLDLASKMPS PRTLKTHLPA QLLPPSFWKE NSKIIYVARN PKDCLVSYYH FSRMTKMMPD
     PGTWEEYIES FKTGKVLWGS WYNHVKGWWD AKDKHHILYL FYEDMKEDPK REIQKILKFL
     EKEMPEEVLN KILYHISFDV MKQNPMANYT TLPTILMDQP ISPFMRKGMP GDWKNYFTVA
     QNEEFDKDYQ KKMAGSTLTF RTEI
//