ID A0A2Y9KEG9_ENHLU Unreviewed; 334 AA.
AC A0A2Y9KEG9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protein eva-1 homolog C isoform X4 {ECO:0000313|RefSeq:XP_022371901.1};
GN Name=LOC111155788 {ECO:0000313|RefSeq:XP_022371901.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022371901.1};
RN [1] {ECO:0000313|RefSeq:XP_022371901.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022371901.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the EVA1 family.
CC {ECO:0000256|ARBA:ARBA00006023}.
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DR RefSeq; XP_022371901.1; XM_022516193.1.
DR AlphaFoldDB; A0A2Y9KEG9; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR CDD; cd22829; Gal_Rha_Lectin_EVA1_EVA1C_rpt2; 1.
DR Gene3D; 2.60.120.740; -; 1.
DR InterPro; IPR039500; EVA1_dom.
DR InterPro; IPR000922; Lectin_gal-bd_dom.
DR InterPro; IPR043159; Lectin_gal-bd_sf.
DR PANTHER; PTHR48334:SF1; PROTEIN EVA-1 HOMOLOG A; 1.
DR PANTHER; PTHR48334; PROTEIN EVA-1 HOMOLOG B-RELATED; 1.
DR Pfam; PF14851; FAM176; 1.
DR Pfam; PF02140; Gal_Lectin; 1.
DR PROSITE; PS50228; SUEL_LECTIN; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..153
FT /note="SUEL-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50228"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..276
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 37500 MW; 5973D41F37F45669 CRC64;
MLLPGHARPP PAPQPAQHPG PRRQVEPPGQ LLRLFYCTVL VCSKEIAALT DFSDELKNKT
VCEDQELKLH CHPSKFLNIY SASYGRRTQE RDTCASEAER LPPFDCLSYW ALQVLSRRCY
GKQRCKIMVN DHHFGSPCPP GVKKYLTVTY ACVPKNILSA IDPAVTNVKP SLKQKDGEHG
INFDPSKPRV LRKDGIIVSN SLAAFAYIRA HPERAALLFV SSICIGLALT LCALVVKVSC
TKDFRELQLV REHLVPESDK AEEDSEDEDG EEDSSDSDFP GERSGFCRTS YPVYSSIEAA
ELAERIERRE QIIQEIWMNS GLDTSLPRNM GQFY
//
