ID A0A2Y9KGQ5_ENHLU Unreviewed; 319 AA.
AC A0A2Y9KGQ5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Bridging integrator 3 {ECO:0000313|RefSeq:XP_022368545.1};
GN Name=LOC111153683 {ECO:0000313|RefSeq:XP_022368545.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022368545.1};
RN [1] {ECO:0000313|RefSeq:XP_022368545.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022368545.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_022368545.1; XM_022512837.1.
DR AlphaFoldDB; A0A2Y9KGQ5; -.
DR STRING; 391180.A0A2Y9KGQ5; -.
DR KEGG; elk:111153683; -.
DR OrthoDB; 3075274at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0051666; P:actin cortical patch localization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd07590; BAR_Bin3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR046982; BIN3/RVS161-like.
DR InterPro; IPR037428; Bin3_BAR.
DR PANTHER; PTHR47174; BRIDGING INTEGRATOR 3; 1.
DR PANTHER; PTHR47174:SF3; BRIDGING INTEGRATOR 3; 1.
DR Pfam; PF03114; BAR; 1.
DR SMART; SM00721; BAR; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51021; BAR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT DOMAIN 75..298
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 90..117
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 187..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 319 AA; 36587 MW; B0D4A060A14B4DD8 CRC64;
MDIAGSHVAL SRGQRSQPYP NILVSCQHET SFLSNQSDPA QPEPHRRSLC ASPSSPGQGD
PAIPHTHQHT WGSQKRVLGA KAIAPVERDF EREYGKLQQL EEQTRRLQKD MKKSTDADLA
MSKSAVKISL DLLSNPLCEQ DQDFLNMVTA LDTAMKRMDA FNQEKVNQIQ KTVIEPLKKF
GSVFPSLNMA VKRREQALQD YRRLQAKVEK YEEKEKTGPV LAKLHQAREE LRPVRDDFEA
KNKQLLDEMP RFYHSRLDYF QPSFEALIRA QVGYYSEMQK IFGDLTQQLD QPGHPDEQRE
RENEARLSEL RALSIVADD
//
