ID A0A2Y9KIZ9_ENHLU Unreviewed; 236 AA.
AC A0A2Y9KIZ9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=cAMP-responsive element modulator {ECO:0000256|ARBA:ARBA00039496};
GN Name=LOC111155537 {ECO:0000313|RefSeq:XP_022371434.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022371434.1};
RN [1] {ECO:0000313|RefSeq:XP_022371434.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022371434.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family.
CC {ECO:0000256|ARBA:ARBA00007163}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022371434.1; XM_022515726.1.
DR AlphaFoldDB; A0A2Y9KIZ9; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd14690; bZIP_CREB1; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR003102; CREB1-like_pKID.
DR InterPro; IPR001630; Leuzip_CREB.
DR PANTHER; PTHR45879:SF4; CAMP-RESPONSIVE ELEMENT MODULATOR; 1.
DR PANTHER; PTHR45879; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF02173; pKID; 1.
DR PRINTS; PR00041; LEUZIPPRCREB.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS50953; KID; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 55..114
FT /note="KID"
FT /evidence="ECO:0000259|PROSITE:PS50953"
FT DOMAIN 178..229
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 19..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 196..230
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 236 AA; 26370 MW; DA77583069EBD98B CRC64;
MSKCGRKKYI KTNLRQMTME TIESQQDGSV TESVAESESA HMQTQTGQNS IPTLAQVATI
AETDESAESE GVIDSHKRRE ILSRRPSYRK ILNELSSDVP GVPKIEEEKS EEEGTPPNIA
TMAVPTSIYQ TSTGQYTATG DMPTYQIRAP TTALPQGVVM AASPGSLHSP QQLAEEATRK
RELRLMKNRE AARECRRKKK EYVKCLENRV AVLENQNKTL IEELKALKDL YCHKAE
//
