ID A0A2Y9KTG0_ENHLU Unreviewed; 626 AA.
AC A0A2Y9KTG0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Sushi domain-containing protein 5 {ECO:0000313|RefSeq:XP_022377041.1};
GN Name=LOC111158986 {ECO:0000313|RefSeq:XP_022377041.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022377041.1};
RN [1] {ECO:0000313|RefSeq:XP_022377041.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022377041.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR RefSeq; XP_022377041.1; XM_022521333.1.
DR AlphaFoldDB; A0A2Y9KTG0; -.
DR STRING; 391180.A0A2Y9KTG0; -.
DR KEGG; elk:111158986; -.
DR OrthoDB; 5351507at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000538; Link_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR32493; SUSHI DOMAIN-CONTAINING PROTEIN 5; 1.
DR PANTHER; PTHR32493:SF0; SUSHI DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00084; Sushi; 1.
DR Pfam; PF00193; Xlink; 1.
DR SMART; SM00445; LINK; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 1.
DR PROSITE; PS50963; LINK_2; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..626
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016013813"
FT TRANSMEM 572..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..127
FT /note="Link"
FT /evidence="ECO:0000259|PROSITE:PS50963"
FT DOMAIN 131..192
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 217..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..235
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 67258 MW; F9C802399E8D1B94 CRC64;
MAAEGRGPRT QLWAAALLLL GLPRLSVRAD GKLFVLESQN GSQGLELEVA QLSCKSRGAH
LVSAEELRTV VQDCAFAVCT TGWLADGTLG TTVCSKGSDE QQIMRAIDVR IESNPAPGAT
YSALCIKDEE KPCGDPPSFP HTILQGRTGL EMGDELLYVC APGHVTGHRE TAFTLLCNSC
GEWYGLVQAC GKDVAEAHID YEDNFPDDRS MSFRELMEDS RTEAEEDRGP GEAPEEVSKQ
DPLVSISVGR ENIAQDTASV PTTGLSIVGS SVPTDSPGTQ LNQKYLFWFP AENFHKPGLQ
KEMNDGSKKQ FLARDNRSSL TAAPGEPEAK VIYSSTHGPS GPFLGRTDSK TGDPMVSSSD
ESWLDGYPVT DGAWRKIEAE EEEEEEDGDK GDASVGLEER VPVTANQPIP VEVKNPRSTS
FTPSEDVTRS SVFPSQTLDV EALALRPGNV SETEGPSTGD GDLIRYQSTV PWSFAAETSP
MATLPYELPS STLGTVTTAV QQMPNHSPST IMAASQTPGE TIAPEVQDGF PYLLSEDFLG
QESPGPGASE ELLPTVESCV GDGCPSLSRG PVIATIVTIL CLLLLLAGVG AVWGHRKCQH
KSSVYKLNVG QRQARHYHQQ IEMEKV
//
