ID A0A2Y9KU30_ENHLU Unreviewed; 710 AA.
AC A0A2Y9KU30;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN Name=LOC111159386 {ECO:0000313|RefSeq:XP_022377512.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022377512.1};
RN [1] {ECO:0000313|RefSeq:XP_022377512.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022377512.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|RuleBase:RU362056}.
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DR RefSeq; XP_022377512.1; XM_022521804.1.
DR AlphaFoldDB; A0A2Y9KU30; -.
DR STRING; 391180.A0A2Y9KU30; -.
DR KEGG; elk:111159386; -.
DR OrthoDB; 2874223at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF87; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Transmembrane {ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362056};
KW Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 117..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 185..206
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 227..255
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 275..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 407..433
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 561..578
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 598..615
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 652..674
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 77035 MW; D3298C59FBF90296 CRC64;
MGPRIGPVGE EPQMPGKDAK AIMGAEDTPG GKASPNPQDL RRSVFYSIKF FVLCHSLLQL
AQLMISGYLK SSISTVEKRF GLSSQTSGLL AAFNEVGNTA LIVFVSYFGS RVHRPRLIGY
GAVLVALAGL LMSLPHFISE PYRYDHTSSV DMPQDFEASL CQPTTSVPAP TPDPSNSSCS
SYMEAQHLAV VGIMFTAQTL LGVGAVPIQP FGISYIDDFA HNSNSPLYVG ILFAVTMMGP
GMAYGLGGLM LRLYVDIDRM PEGGISLTSK DPRWVGAWWL GFLISAGAVA LAAVPYFFFP
REMPREKHEL RFRRRILETT ASSVSKGEDS PSESPAESQE KQDSLTQIAP DLTVIQFIKV
FPRVLLRTLR HPIFLLVVLS QVCMSSMVAG MATFLPKFLE RQFSVTASYA NLLIGCLTIP
LAIVGIVVGG VLVKRLHLGP VRCAVLCLLG ALFCLLLSLP LFFMGCSTHQ IAGITHLPGH
LPGPELFTAC TEPCFCPLDD FNPVCDPRTH VEYLTPCQAG CTGRAVQEAL DKSQVFYTNC
SCVVGGGPVL AGSCESPCSH LVLPFMLLVS LGAALASLTH TPSFMLILRG VKKEDKTLAV
GIQFMLLRVL AWMPSPVIHG SAIDTTCVHW AQSCGRRAVC RYYDHDLLRN RFVGLQVFFK
TGSLACFALI LAILRQQDKD EGTQVTVSTS GLQQQLLTSG PEKKPEESRV
//
