ID A0A2Y9L0R0_ENHLU Unreviewed; 315 AA.
AC A0A2Y9L0R0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Leukocyte antigen CD37 isoform X1 {ECO:0000313|RefSeq:XP_022379506.1, ECO:0000313|RefSeq:XP_022379507.1};
GN Name=LOC111160602 {ECO:0000313|RefSeq:XP_022379506.1,
GN ECO:0000313|RefSeq:XP_022379507.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022379506.1};
RN [1] {ECO:0000313|RefSeq:XP_022379506.1, ECO:0000313|RefSeq:XP_022379507.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022379506.1,
RC ECO:0000313|RefSeq:XP_022379507.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840}.
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DR RefSeq; XP_022379506.1; XM_022523798.1.
DR RefSeq; XP_022379507.1; XM_022523799.1.
DR STRING; 391180.A0A2Y9L0R0; -.
DR KEGG; elk:111160602; -.
DR OrthoDB; 5359808at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03160; CD37_CD82_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282:SF263; LEUKOCYTE ANTIGEN CD37; 1.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 277..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 35092 MW; A0E4DF6790CA945B CRC64;
MSAQDSCLSL IKYLLFVFNL FFFVLGSLIF CFGIWILIDK TSFVSFVGLS FVPLQIWSKA
LAISGILTMG LALLGCVGSL KELRCLLGLY FGILLLLFAT QITLGILIST QRMRLERRVK
EIVLETIQNY RSRPEESAAE ESWDYVQFQL RCCGWNSPRD WFSIPSLISN ESEVHRVPCS
CYNSSATNDS AVFDKLSFPQ FSRPGPLARP RHSTDLCVVP ADSNVYSEGC ARSLQKWLHN
NLISIVGICL GVGLLEVIWS SPHSQLALQS LDGPTPNPWE RCKPARASAH PGSPASPHVR
GRPTPCKPRL AARRK
//
