ID A0A2Y9L254_ENHLU Unreviewed; 336 AA.
AC A0A2Y9L254;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=CMRF35-like molecule 8 {ECO:0000313|RefSeq:XP_022375555.1};
GN Name=LOC111158046 {ECO:0000313|RefSeq:XP_022375555.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022375555.1};
RN [1] {ECO:0000313|RefSeq:XP_022375555.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022375555.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the CD300 family.
CC {ECO:0000256|ARBA:ARBA00043958}.
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DR RefSeq; XP_022375555.1; XM_022519847.1.
DR AlphaFoldDB; A0A2Y9L254; -.
DR STRING; 391180.A0A2Y9L254; -.
DR KEGG; elk:111158046; -.
DR OrthoDB; 3031152at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05716; IgV_pIgR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR11860:SF116; CMRF35-LIKE MOLECULE 8; 1.
DR PANTHER; PTHR11860; POLYMERIC-IMMUNOGLOBULIN RECEPTOR; 1.
DR Pfam; PF15330; SIT; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..336
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016041316"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..108
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 151..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 336 AA; 37125 MW; 59743D8DE4854489 CRC64;
MTQRARIPWL SWALLLLWVP GCWSLSGPTS VTGTMGGSVS VQCQYEEEFT ENAKYWCKSL
CVWKIVKTKG TDREVRKGRV SIRDHPANLT FTVTLESLTE DDAGMYLCGI DSSLLPGYLF
DDTFQVVLSV TPATTPASPV SITVTQMSTT TAKITTSPSP PSSAAPTAEG ATCSAGSGEE
FPPSQGLRLQ VLLSLLALLL LLLGGSSLLT WRMVCRRVKS GENPKQPRFP GQQEEPHYEN
LELQTWPLRE EPMHPRQPEV EYSTVKTPRE EPHYSTVVFG FQSGGSEANS IRSQRTLDKE
TQYSCSPRRS PIRQLGAISV VGFVEDEWEW DSSGDL
//
