ID   A0A2Y9LA75_ENHLU        Unreviewed;       498 AA.
AC   A0A2Y9LA75;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Lymphoid-restricted membrane protein isoform X2 {ECO:0000313|RefSeq:XP_022378363.1, ECO:0000313|RefSeq:XP_022378365.1};
GN   Name=LOC111159949 {ECO:0000313|RefSeq:XP_022378363.1,
GN   ECO:0000313|RefSeq:XP_022378365.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022378365.1};
RN   [1] {ECO:0000313|RefSeq:XP_022378363.1, ECO:0000313|RefSeq:XP_022378365.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022378363.1,
RC   ECO:0000313|RefSeq:XP_022378365.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022378363.1; XM_022522655.1.
DR   RefSeq; XP_022378365.1; XM_022522657.1.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008677; MRVI1.
DR   PANTHER; PTHR15352:SF3; INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2-RELATED; 1.
DR   PANTHER; PTHR15352; LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1; 1.
DR   Pfam; PF05781; MRVI1; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        439..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          380..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..407
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  56099 MW;  C4778DBBFF0F3787 CRC64;
     MNDDLRMEEN GVDHLYSESL PQSRECSTLS SPGHTLSTES TITSSDSGSE ILNMASDDLD
     YKSLCEKEED TRSASGMIKI TGKSASPENI ALQGSVSEDK TMLNLEAKEE PVTIDEHRKE
     CAARDTAVSF LPVTTVKSIN FRQSDNTSAN EKEVEAEFLR LSLGFKCDWF TLEKRVKLEE
     RSRDLAEENL KKEITNCLKL LESLTPLCED DNHAQEIVKK LEKSITLLSQ CTARVASKAE
     MLGAINQESR VSKAVEVMIQ HVENLKRMYA KEHAELEELK QVLLQNERSF NPLEDEDDCQ
     IKKRSSSLNS KPSSLRRVTI ASLPRNIGNA RMVAGMENDR FGRRSSSWRI LGSKQSEHRP
     SLHRFISTYS WADAEEEKCE LKTKDDSEPP GEEIAERTRK PSLSEKRNNP SKWDGSSLYD
     TVAAWATNLK TSFRKANKAL WISAVFIVLF AALMSFLTGR LFQKSVDAAP IPDGDSWMSL
     EQILWPFTRL QHNGPPPV
//