ID A0A2Y9LCM0_DELLE Unreviewed; 970 AA.
AC A0A2Y9LCM0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Seizure 6-like protein isoform X5 {ECO:0000313|RefSeq:XP_022406491.1};
GN Name=SEZ6L {ECO:0000313|RefSeq:XP_022406491.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022406491.1};
RN [1] {ECO:0000313|RefSeq:XP_022406491.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022406491.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR RefSeq; XP_022406491.1; XM_022550783.2.
DR AlphaFoldDB; A0A2Y9LCM0; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 4.
DR CDD; cd00041; CUB; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 4.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF8; SEIZURE 6-LIKE PROTEIN; 1.
DR Pfam; PF00431; CUB; 3.
DR Pfam; PF00084; Sushi; 4.
DR SMART; SM00032; CCP; 4.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 4.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 3.
DR PROSITE; PS50923; SUSHI; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..970
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015926313"
FT TRANSMEM 903..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 291..399
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 401..460
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 462..572
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 575..636
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 638..749
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 753..812
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 817..878
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 29..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 291..318
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 462..489
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 783..810
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 970 AA; 105228 MW; 4641E7E41883506F CRC64;
MPAARPPAAG PGGIALLLAL LLGSPAAAPA EDAPLEGDAG PSGTYFLPLE ALGSSSLSHE
TPKERVTTAP LNPAQSGDEL HKPELEGMVP SAPQDSAAAS MLLPLPEEPG TGHAFPPTKK
PPSLKQVNLT RRQLRPKATT AAAVQRAASQ PASSDLVLLS SATEKLRPPG DQDPVASTGE
GTHPLSLSSE EPLWLEQKEG AVPTTPAPLQ IAPFTSQPLV AHTLPQSPDP GAPAVPEEAH
EAPPGDASPM TLMDKCENEL TGSASEESQE TTTSTIITTT VITTEQAPAL CSVSFSDPEG
YIDSSDYPPL PLNNFLECTY NVTVYTGYGV ELQVKSVNLS EGELLSIRGV DGPSLTILAN
HTLLVEGQVI RSPTNTISVY FRTFQDDGLG TFQLHYQAFM LSCSFPRRPD YGDVMVMDLH
SGGVAHFHCH LGYELQGAKT LTCINASKPH WSSQEPICSA PCGGAVHNAT IGRVLSPSHS
GNTNGSQFCV WTIEAPEGQK LHLHFEKLSL HEKDRMMVYS GLTNKSTLLY DSLQTENVPF
EGLLSDGHTI CIEFTSDQGR VASAFNIRFE AFEKGHCYEP YIQNGNFTTS DPTYNIGTIV
EFTCDPGHSL EQGPAIIECI NVRDPYWNDT EPLCRAMCGG ELSAVAGVVL SPNWPEPYVE
GEDCVWKIHV GEEKRIFLDI QFLNLSNSDI LTIYDGDEVM PHILGQYLGN SGPQKLYSST
PDLTIQFHSD PAGLIFGKGQ GFIMNYIEVS RNDSCSDLPE IQNGWKTTSH TELVRGARIT
YQCDPGYDIV GSDTLTCQWD LSWSSDPPFC EKTEESLACD NPGLPENGYQ ILYKRLYLPG
ESLTFMCYEG FELMGEVTIR CILGQPSHWN GPLPVCKVNQ DSFEHALEVA EAAAETSLEG
GNVALAIFIP ALLISLLLGG AYIYITRCRY YSNLRLPLMY SHPYSQITVE TEFDNPIYET
GETREYEVSI
//
