ID A0A2Y9LED8_ENHLU Unreviewed; 563 AA.
AC A0A2Y9LED8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Myc box-dependent-interacting protein 1 isoform X2 {ECO:0000313|RefSeq:XP_022379925.1};
GN Name=LOC111160844 {ECO:0000313|RefSeq:XP_022379925.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022379925.1};
RN [1] {ECO:0000313|RefSeq:XP_022379925.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022379925.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022379925.1; XM_022524217.1.
DR AlphaFoldDB; A0A2Y9LED8; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0030100; P:regulation of endocytosis; IEA:InterPro.
DR CDD; cd07611; BAR_Amphiphysin_I_II; 1.
DR CDD; cd12139; SH3_Bin1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR035471; Amphiphysin-2_SH3.
DR InterPro; IPR003023; Amphiphysin_2.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF4; MYC BOX-DEPENDENT-INTERACTING PROTEIN 1; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR PRINTS; PR01253; AMPHIPHYSIN2.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 29..245
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 490..563
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 248..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 248..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 61463 MW; 46CD1FDE27F7F2B4 CRC64;
MAEMGSKGVT AGKIASNVQK KLTRAQEKVL QKLGKADETK DEQFEQCVQN FNKQLTEGTR
LQKDLRTYLA SVKAMHEASK KLNECLQEVY EPDWPGRDDA NKIAENNDLL WLDYHQKLVD
QALLTMDTYL GQFPDIKSRI AKRGRKLVDY DSARHHYESL QTAKKKDEAK IAKAEEELIK
AQKVFEEMNV DLQEELPSLW NSRVGFYVNT FQSIAGLEEN FHKEMSKLNE SLNDVLVSLE
KQHGSNTFTV KAQPSDNAPA KGNKSPSPPP DGSPAATPEI RVNHEPEPPS SATAGASLPK
SPSQLRKGPP VPPPPKHTPS KEVKQEQILS LFDDTFVPEI SVTTPSQFEA PGPFSEQASL
LDLDFDPLPP VASPVKAPTP SGQSIPWDLW EPTESPAGSL PSREPSAAEG TFAVAWPSQT
VEPGPAQPAE ASEVAGGTQP AAGAQEPGET AASEAASSSL PAVVVETFSA TVNGTVEGGS
GAGRLDLPPG FMFKVQAQHD YVATDTDELQ LKAGDVVLVI PFQNPEEQDE GWLMGVKESD
WNQHKELEKC RGVFPENFTE RVQ
//
