ID   A0A2Y9LLJ8_ENHLU        Unreviewed;       478 AA.
AC   A0A2Y9LLJ8;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Noelin-2 isoform X1 {ECO:0000313|RefSeq:XP_022382620.1};
GN   Name=LOC111162470 {ECO:0000313|RefSeq:XP_022382620.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022382620.1};
RN   [1] {ECO:0000313|RefSeq:XP_022382620.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022382620.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC       {ECO:0000256|ARBA:ARBA00034103}.
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DR   RefSeq; XP_022382620.1; XM_022526912.1.
DR   AlphaFoldDB; A0A2Y9LLJ8; -.
DR   KEGG; elk:111162470; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022082; Noelin_dom.
DR   InterPro; IPR003112; Olfac-like_dom.
DR   PANTHER; PTHR23192:SF27; NOELIN-2; 1.
DR   PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR   Pfam; PF12308; Noelin-1; 1.
DR   Pfam; PF02191; OLF; 1.
DR   SMART; SM00284; OLF; 1.
DR   PROSITE; PS51132; OLF; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW   ProRule:PRU00446}; Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..478
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016148661"
FT   DOMAIN          218..470
FT                   /note="Olfactomedin-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51132"
FT   COILED          170..216
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   DISULFID        219..401
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
SQ   SEQUENCE   478 AA;  53843 MW;  17363697D6BA657B CRC64;
     MSVPLLKIGA VLSTMAMVTN WMSQTLPSLV GLNGTVSRAG ASEKITLFQS PEEGWQLYTS
     AQAPDGKCIC TAVIPAQSTC SRDGRSRELR QLMEKVQNVS QSMEVLELRT YRDLQYVRSM
     ETLMRSLDAR LRAADGSLST KSFQELKDRM SELLPLSSVL EQYKADTRTI VRLREEVRNL
     SSSLAAIQEE MGAYGYEDLQ QRVMALEARL HACAQKLGCG KLTGVSNPIT IRAMGSRFGS
     WMTDTMAPSA DSRVWYMDGY YKGRRVLEFR TLGDFIKGQN FIQHLLPQPW AGTGHVVYNG
     SLFYNKYQSN VVVKYHFRSR SVLVQRSLPG AGYNNTFPYS WGGFSDMDFM VDESGLWAVY
     TTNQNAGNIV VSRLDPHTLE VVRSWDTGYP KRSAGEAFMI CGVLYVTNSH LAGAKVYFAY
     FTNTSSYEYT DVPFHNQYSH ISMLDYNPRE RALYTWNNGH QVLYNVTLFH VISTAGDP
//