ID A0A2Y9LPM5_DELLE Unreviewed; 547 AA.
AC A0A2Y9LPM5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ETS-related transcription factor Elf-2 isoform X5 {ECO:0000313|RefSeq:XP_022410671.1};
GN Name=ELF2 {ECO:0000313|RefSeq:XP_022410671.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022410671.1};
RN [1] {ECO:0000313|RefSeq:XP_022410671.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022410671.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_022410671.1; XM_022554963.2.
DR AlphaFoldDB; A0A2Y9LPM5; -.
DR Ensembl; ENSDLET00000028883; ENSDLEP00000026261; ENSDLEG00000019002.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR022084; TF_Elf_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF10; ETS-RELATED TRANSCRIPTION FACTOR ELF-2; 1.
DR Pfam; PF12310; Elf-1_N; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 161..243
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 88..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 58540 MW; 7B9B5BBAA21B4CF1 CRC64;
MATSLHEGPT NQLDLLIRAV EASVHSSNAH CTDKTIEAAE ALLHMESPTC LRDSRSPVEV
FVPPCVSTPE FIHAAMRPDV ITETVVEVST EESEPMDTSP LPTSPDSHEP MKKKKAQRAS
QIIRSSAIVG RKPKTQQSPI SNGSPELGIK KKPREGKGNT TYLWEFLLDL LQDKNTCPRY
IKWTQREKGI FKLVDSKAVS KLWGKHKNKP DMNYETMGRA LRYYYQRGIL AKVEGQRLVY
QFKDMPKNIV VIDDDKSEAC NEDVATAAAG ESLERVSLSA ESLLKAAASV RGGKNSSPLN
CSKAEKGVAR VVNITPPGHE ASSRSPTTTA SVSATAAPRT VRVAMQVPVV MTSLGQKIST
VAVQSVNAGA PLITSSSPTT AASPKVVIQT IPTVVPASTE NADKITMQPA KIITIPATQL
AQCQLQTKSN LPGSGSINIV GTPLAVRALT PVSIAHGAPV MRLAVPPQQA SGQTPPRVIS
AVIKGPEIKS EAVAKKQEHD VKTLQLVQEE KPADGNKTVT HVVVVSAPSA LALPVTMKTE
GLVTCEK
//
