ID   A0A2Y9LQL0_DELLE        Unreviewed;      1822 AA.
AC   A0A2Y9LQL0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Protein NLRC5 isoform X4 {ECO:0000313|RefSeq:XP_022411665.1};
GN   Name=NLRC5 {ECO:0000313|RefSeq:XP_022411665.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022411665.1};
RN   [1] {ECO:0000313|RefSeq:XP_022411665.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022411665.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022411665.1; XM_022555957.1.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.533.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 8.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041210; NLRC5_atypical_Card.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF284; RIBONUCLEASE_ANGIOGENIN INHIBITOR 1; 1.
DR   Pfam; PF18461; Atypical_Card; 1.
DR   Pfam; PF13516; LRR_6; 5.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   SMART; SM00368; LRR_RI; 15.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 3.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   DOMAIN          235..368
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          115..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1822 AA;  199577 MW;  A3A7742867E07C0C CRC64;
     MMNQEARAGL LTDPISLQLG TENLCGCLVR LLSKDPEWLS AKMKFFLPNM DLGSGDQSPD
     PTQRVIQQLS KLHTQGQSTW QEFIHCVCME LDVPLDLEVP LLSIWGHGDG FPRQLDIGEE
     SQPDSQLHPG LKRPHQSCGS SPRPKQFKKQ EQELAKRYLQ LLRTSARQRY ADRTPRPGQP
     LAFPQVYIPP ILQWSRASAP FDAQEGAVTG DPKAEDGTDV NIRDLFNTKA NRGPRVMVLL
     GKAGMGKTTL AHRLCQKWAD GQLDRFQALF LFEFRQLNVI TGFLTLPQLL FDLYLRPEAG
     PEAVFEYLQE NANGTLLIFD GLDEVFHPCP SKETAGPEDP ASALTLFSRL CRGTLLPGCW
     VMATSRPGKL PACLPTEVAT VHMWGFDGPR VEEYVSRFFS DQPSQEAALA ELRADRRLWS
     MCALPALCRV ACLCLYHLLP GSSPGQSAAL LPTMTQNYVQ MVLTLSPQGF LPAESLLGLG
     EVALRGLETG KIIFSAGDIP PPVMAFGAAL GLMTSCVCMG PGHQETGYAF THLSLQEFFA
     ALHLMASPQV DKDTLSQHVT LTSRWVQRSK ARLGLIDHLP TFLAGLASCA CRPFLSLLAQ
     QDEAWVGTKQ AAVVQALRKL ATRRLTGPKV VELCHCVGET QVPELAGFTA QSLPHQMPFH
     NFLLTYTDLA ALTNILGHRD APIHLDFEGC PLEPRCPEAL AGCGQVENLS FKSRKCGDAF
     AKALSRCLPT MGSLKKLGLA GSKITAQGIS HLVQALPLCP QLEEISFRDN QLKDWEVLSI
     VEVLPCLPRL RKLDLSLSNV SVSTLLSLTN VAVTCPTVRM LQVRKADLIF LLSPPTETAT
     ELQGDPDLRG NANQRKEAQR RSLALRLQKC QLGVHDVEVL IAQLREGPHL DEVDLSGNQL
     EDEGCQLMAE AAPQLHIARK LDLSSNGLSL AGACRVLSAV SMCRTLAELH VSLLHKTVVL
     KFAPEPEEQE VIQKRAAFPG SLTFQMPSDP LPCAPRIRLT HCALQAQHLE HLCKALGGSC
     CLRHLDLSGN ALGDKGVALL AQLLPGLGAL QSLNLSENDL SLDAVFSLTR CFSTLPWLVH
     LDFSSESQSV ILRGDGRDRD LSAAGSLPEF QAGAQFLGFG QRRISRSFCL RECQLEPLSL
     SRLCETLEKC PGPLEVKLSC KVLSDQSLET LLHHLPRLPE LSLLQLTQME LSPRSPLLLA
     DIFSLCPRVQ KVDLRSLHHA TLHFRSSEEQ EGGCCGRFTG CGLSQEHVEP LCWLLSKCED
     LSQLDLSANL LGDAGLRCLL ECLPQVPISG SLNLSHNGVS QESVLYLVET LPSCPRIREA
     SVNLGSKQSF WVHFSRQEEA RKTLRLSECS FRPEHVPRLA TGLSQALWLT ELTLTQCFLG
     LEQLTILLGL LKWPAGLLTL RVEEPWVGKA GVLTLLEVCA QASGNVTEIS ISETQQQLCI
     QLEFPHQENP EATTLRLAHC DLGTHHSLLA RQLMETCARL RQLSLSQVNL CEASALLLQS
     LLLSLSELKN FRLTSSCVSS SALAHLTSGL SHCHHLEELD LSNNQLGEEG TKVLTGALEG
     KCWLKRLDLS HNQIGDTGAQ NLAAVLPGLP ELRKIDLSAN GIGPAGGARL AECLPLCRHL
     EELMLGYNAL GDPTALGLAR GLPRHLRVLH LTSSHLGPEG ALSLGQALDG CPHMEEISLA
     ENNLAGGVPH FHLGLPLLRQ IDLVSCEIDN QTAKPLTASF VLCPALEEIM LSWNLLGDDA
     AAELARVLPQ MGRLKRMDLE KNRITAYGAW LLAEGLAQGS GIQVIRLWNN PIHPEMVERL
     QSQEPRLDFA FFDNQPQVPH GT
//