ID A0A2Y9LT19_DELLE Unreviewed; 1003 AA.
AC A0A2Y9LT19;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Sorting nexin-19 isoform X6 {ECO:0000313|RefSeq:XP_022411876.1};
GN Name=SNX19 {ECO:0000313|RefSeq:XP_022411876.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022411876.1};
RN [1] {ECO:0000313|RefSeq:XP_022411876.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022411876.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR RefSeq; XP_022411876.1; XM_022556168.2.
DR AlphaFoldDB; A0A2Y9LT19; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF31; SORTING NEXIN-19; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..286
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 492..645
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1003 AA; 109895 MW; C8084B4204B7B9D3 CRC64;
MEEGAAGPGS PLPPAMKAET ATAAQKPPAG PSLSHLLSSR KLVALGAVLG WLLVIHLLVN
VWLLCLLSAL LLVLGGWLGA DAIVGPSGRL HLERFIPMAV CPPNPEAERQ LEQEIDRTIR
MVMRDFVSSW YRTVSQEPAF EEEMEAAMRG LVQELRRRMA RVDSHALAQR VLTLCGCHLQ
SYLQAKEATT GKQSGIDEPS QLWEAYCQAT APHPAVQSPR AEVAYTRGIV NVLLQGLVPK
PHLETRTGRH VVVELITCNV MLPLISKLSD PDWIHLVLVG IFSKARTGPE GVGKPLCPAS
ALEQPSVPTS LPLIVEVQSL ADARAPSPAP VLLNYSEPSH PSPEVEEGRE ALEGDLGGVL
EEREVGNNSS HFLQPLFLSE DAELESPLSE LGKETIMLVN PGTFLSARIQ DSLCALGGSQ
ALESKDEEGS EGIEGAEAEE GPGTETETGL LVSMLNSCPE IQIDTVDKDE EQGDVTSLTT
LLASPERMCP PRPSCLEKDL TDGVSSLDPS LPQYETALDC ESSSGLQQLA YHTVNRRYRE
FLNLQTRLEE KSDLRKFIKS QELPQPQNAC LLFTSSHPDL RGWRPVDVKG PKKLFPDLPF
GNMDSDRVEA RKSLLESFLK QLCAIPEIAN SEEMQEFLAL NTDARIAFVK KPFVVSRIDK
VVVSAIVDTL KTAFPRSEPQ SPTEELSEAE TESKPQPEGK KATKSRLRFS SSKIAPALNI
TEAHEKILYC LREGSVESEI LSMSGMESFI EKQTKLLETQ PAEAPGKDSE QISKGCVDDC
VSGAALPAQD LSNSDPGTET ELADTALDLL LLLLMEQWRW LCTENVQKVL RLIFGTLIQR
WLEVQVATLT CPQRWVQYLR LLQESIWPGG LLPEYPRPVR TKEQKAAAEK QALQSLMGVL
PDIVVEILGA NKCRLSWSLV LESLQQPLIN RPVLPDNLPA PLTVSAHSRT SRLLALPHHR
HLIYCLWDVI LEFLDLSASA EVSAITSSAA DTPGSPRKMG ISP
//
