ID A0A2Y9LUF6_DELLE Unreviewed; 469 AA.
AC A0A2Y9LUF6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Interferon gamma receptor 1 {ECO:0000313|RefSeq:XP_022413334.1};
GN Name=IFNGR1 {ECO:0000313|RefSeq:XP_022413334.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022413334.1};
RN [1] {ECO:0000313|RefSeq:XP_022413334.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022413334.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the type II cytokine receptor family.
CC {ECO:0000256|ARBA:ARBA00005399}.
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DR RefSeq; XP_022413334.1; XM_022557626.1.
DR AlphaFoldDB; A0A2Y9LUF6; -.
DR STRING; 9749.A0A2Y9LUF6; -.
DR Ensembl; ENSDLET00000028524; ENSDLEP00000025930; ENSDLEG00000018795.
DR KEGG; dle:111166198; -.
DR InParanoid; A0A2Y9LUF6; -.
DR OrthoDB; 5356432at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019955; F:cytokine binding; IEA:InterPro.
DR GO; GO:0004906; F:type II interferon receptor activity; IEA:Ensembl.
DR GO; GO:0038196; P:type III interferon-mediated signaling pathway; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR021126; IFN_gamma_rc_D2_pox/mammal.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008355; Interferon_gamma_rcpt_asu.
DR PANTHER; PTHR20859:SF5; INTERFERON GAMMA RECEPTOR 1; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF07140; IFNGR1_D2; 1.
DR Pfam; PF20634; IFNGR1_transm; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR PRINTS; PR01777; INTERFERONGR.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_022413334.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..469
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015970669"
FT TRANSMEM 245..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..109
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 129..234
FT /note="Interferon gamma receptor D2"
FT /evidence="ECO:0000259|Pfam:PF07140"
FT REGION 322..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 51702 MW; D8776CA14F18BA87 CRC64;
MALFLLLVLI VQAGSWAEMG AADQKLSSVP TPTNLTIEAY NLNTVLFWDY PIMPWSPVFT
VQVMTYRDGQ WIDACNTSHH SCNIFSIIDD PSSPLWARVK ARLGQEESVY AQSREFILCK
EGRIGPPKLV ITKKEDQIIV DIFHPLITVN ENEPEAIYDD ENTCYTFTYN VFVRINGSET
TNKMYIKKED DCNETQCFLS IPVSSLNSEY CVSAEGVSET WAVTTEKSEE LCITVSDNNS
AENPVWIPIV AALLLFLVLA LVVVCCLVKK MNPFKRENIM LPKSLLSVVK SASSETKSES
KHISPITYQP IAIENEQLSP GTISSVHTED SPGKAEHGED LSSGTQVVMT EENISDLAPG
SSLTPVKGEN SIHASSNQSE TCSITLNVYH ARNGSDSGLV VSGNCSDSEF PPSNKTEIKT
EGRESITLRN TITSFGYDKP HVLVDLLVDE GGKESLIGYR PTADSREFS
//
