ID A0A2Y9LXL3_DELLE Unreviewed; 1513 AA.
AC A0A2Y9LXL3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=SAM and SH3 domain-containing protein 1 isoform X1 {ECO:0000313|RefSeq:XP_022414469.1};
GN Name=LOC111166741 {ECO:0000313|RefSeq:XP_022414469.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022414469.1};
RN [1] {ECO:0000313|RefSeq:XP_022414469.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022414469.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022414469.1; XM_022558761.2.
DR STRING; 9749.A0A2Y9LXL3; -.
DR KEGG; dle:111166741; -.
DR InParanoid; A0A2Y9LXL3; -.
DR OrthoDB; 5403637at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR CDD; cd09527; SAM_Samd5; 1.
DR CDD; cd09559; SAM_SASH1_repeat1; 1.
DR CDD; cd09492; SAM_SASH1_repeat2; 1.
DR CDD; cd11967; SH3_SASH1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037627; SASH1_SAM_repeat1.
DR InterPro; IPR037630; SASH1_SAM_repeat2.
DR InterPro; IPR035720; SASH1_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR021090; SPIDER.
DR PANTHER; PTHR12301:SF3; SAM AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12301; SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF12485; SLY; 1.
DR SMART; SM00454; SAM; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 6..65
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 823..884
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 902..966
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1443..1507
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 76..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 982..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1100..1147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1163..1194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1210..1329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..91
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..804
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..1036
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1106..1120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1284
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1298..1326
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1513 AA; 167190 MW; 00130B304C361EFF CRC64;
MCTNIVYEWL KALQLPQYAE SFVDNGYDDL EVCKQIGDPD LDAIGVLAPA HRRRILEAVR
RLREQDAAAA GLYFTLEPQP PPAPPGPPAV AVPTRRRGEP CGGQAQGPRG DPRSLTTAPR
GRELVSYPKL KLKIMIRDKL VRDGIHLSKP PYSRKDGSLG NIDDLAQQYA DYYNTCFSDV
CERMEELRKR RVSQDLDVEK PEASPTSLQL RSQIEESLGF SSTVSTPEVE RKNPLHKSHS
EDSSVGKGDW KKKNKYFWQN FRKSQKGIMR QTSKGEDVGY VASELTMSDE ERIQLMVMVK
EKMISIEEAL ARVRVQLKEY EAQHRQSAAL DPADWPDGSY PPFDGSSNCN SREQSDDETE
ESVKFKRLHK LVNSTRRVRK KLIRVEEMKK PSPEGGEEQV FENSPVPDER SALYSGVHKK
PFFFDASPEK PPEDDSDSLT TSPSSSSLDT WGAGRKLVKT FSKGESRGLI KPPKKMGTFF
SYPEDDKAQK VSRSLTEGEM KKGLGSLSHG VSTDGVCFYD SHRRRHHLLV SLEEVQSVRK
QIRLKKTDTN YSCSRAFLCQ RPSRKGINST TCDLQLLRQK PKGGGVCGGP GRRVRGRPSV
SEFNVTYVVE RSLYSHLNLT QLVRPASDRT LSKAEKQDLR RCLLEEEETR RKWAATVDRC
TKRVLLRIRQ KSRTCSFGGF DLTNRSLHIG SNNSDPLGKE GDFVYKEVIK SPTASRISLG
KKVKSVKETM RKRMSKKYSS SVSEQDSGLD GMPGSPPSSQ PDSEHMDKPK LKAGGSVESL
RSSLSGQSSM SGQTVSTTDS STSNRESVKS EDGDDEEPPY RGPFCGRARV HTDFTPSPYD
TDSLKLKKGD IIDIISKPPM GTWMGLLNNK VGTFKFIYVD VLNEEEEKPK RPTRRRRKGR
PPQPKSVEDL LDRINLKEHM PTFLFNGYED LDTFKLLEEE DLDELNIRDP EHRAVLLTAV
ELLQEYDSNS DQSGSQEKLL VDSQGLSGCS PRDSGCYESS ENLENGKSRK TSPSAKSSAE
SSVKSFNRNQ LGNYPTLPLT KPVDALKPGG EGRLGSGLTP HTSKHCDPPC VTDLNKNRRS
LPVSICRSCE TLEGPQAVET WPRSHSLDDL QGEPERDVPG EVTEPSPQIV PKVPQKTAPS
ITKVQSPKLD SAVDNALLLT QSKRFSEPQK TTTKKLDGPM AAFSRGTSPP PCLPKTYDAQ
LPAVKHGLTR TPLEGHRKGL DFEGTHHPPG TKEGVDAEQR GPEARSQARP PAQPPPVPAK
KSRERLANGL PPVPPGPPGA PGADVPSLPL KKGSPGGPSD CPLPPVARPP PGPEPGSPPS
ARPPPWLSEL PESASLQEHG VRLGPALARK VSCTRGVDLE MLTEKKLRAE GIDLTEEPYS
DKHGRCGIPE ALVQRYAEDL DQPERDVATN MDQIRVKLLR KQHRMAIPSG GLTEICRKPL
SPGCVSSVSD WLVSIGLPMY ASALTEAGFS TLGQVPSLSH TCLQEAGITE ERHISKLVSA
ARLFKLPPGP EAM
//
