ID A0A2Y9M0T3_DELLE Unreviewed; 997 AA.
AC A0A2Y9M0T3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Liprin-alpha-2 isoform X2 {ECO:0000313|RefSeq:XP_022415634.1};
GN Name=PPFIA2 {ECO:0000313|RefSeq:XP_022415634.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022415634.1};
RN [1] {ECO:0000313|RefSeq:XP_022415634.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022415634.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR RefSeq; XP_022415634.1; XM_022559926.2.
DR AlphaFoldDB; A0A2Y9M0T3; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF6; LIPRIN-ALPHA-2; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 644..710
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 767..824
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 848..917
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 166..207
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 251..281
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 396..437
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 455..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 113915 MW; 2788D93941FD5402 CRC64;
MAQMKERLAA LSSRVGEVEQ EAETARKDLI KTEEMNTKYQ RDIREAMAQK EDMEERITTL
EKRYLSAQRE STSIHDMNDK LENELANKEA ILRQMEEKNR QLQERLELAE QKLQQTMRKA
ETLPEVEAEL AQRIAALTKS DPTSSTSSDD YQYVMEAKLQ EMISIRRKAE ERHGNIEERM
RHLEGQLEEK NQELQRARQR EKMNEEHNKR LSDTVDRLLT ESNERLQLHL KERMAALEEK
NVLIQESETF RKNLEESLHD KERLAEEIEK LRSELDQLKM RTGSLIEPTI SRTHLDTSAE
LRYSVGSLVD SQSDYRTTKV IRRPRRGRMG VRRDEPKVKS LGDHEWNRTQ QIGVLSSHPF
ESDTEMSDID DDDRETIFSS MDLLSPSGHS DAQTLAMMLQ EQLDAINKEI RLIQEEKEST
ELRAEEIENR VASVSLEGLN LARVHPGTSI TASVTASSLA SSSPPSGHST PKLTPRSPAR
EMDRMGVMTL PSDLRKHRRK IAVVEEDGRE DKATIKCETS PPPTPRAVRM THTLPSSYHN
DARSSLTASL EAESLGLGSA NSSQDSLHKT PKKKGIKSSI GRLFGKKEKA RLGQLRGFME
TEAAAQESLG LGKLGTQAEK DRRLKKKHEL LEEARRKGLP FAQWDGPTVV AWLELWLGMP
AWYVAACRAN VKSGAIMSAL SDTEIQREIG ISNPLHRLKL RLAIQEMVSL TSPSAPPTSR
TPSGNVWVTH EEMENLAAPA KTKESEEGSW AQTLAYGDMN HEWIGNEWLP SLGLPQYRSY
FMECLVDARM LDHLTKKDLR VHLKMVDSFH RTSLQYGIMC LKRLNYDRKE LERRREASQH
EIKDVLVWSN DRVIRWIQAI GLREYANNIL ESGVHGSLIA LDENFDYSSL ALLLQIPTQN
TQARQILERE YNNLLALGTE RRLDESDDKN FRRGSTWRRQ FPPREVHGIS MMPGSSETLP
AGFRLTTTSG QSRKMTTDVP SSRLQRLDNS TVRTYSC
//
