ID   A0A2Y9M5U8_DELLE        Unreviewed;       569 AA.
AC   A0A2Y9M5U8;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Dynein regulatory complex subunit 3 {ECO:0000256|ARBA:ARBA00040950};
GN   Name=DRC3 {ECO:0000313|RefSeq:XP_022416451.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022416451.1};
RN   [1] {ECO:0000313|RefSeq:XP_022416451.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022416451.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC       {ECO:0000256|ARBA:ARBA00004611}.
CC   -!- SIMILARITY: Belongs to the DRC3 family.
CC       {ECO:0000256|ARBA:ARBA00038378}.
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DR   RefSeq; XP_022416451.1; XM_022560743.2.
DR   AlphaFoldDB; A0A2Y9M5U8; -.
DR   STRING; 9749.A0A2Y9M5U8; -.
DR   KEGG; dle:111167675; -.
DR   InParanoid; A0A2Y9M5U8; -.
DR   OrthoDB; 24160at2759; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973:SF12; DYNEIN REGULATORY COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF14580; LRR_9; 1.
DR   SMART; SM00365; LRR_SD22; 4.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 4.
PE   3: Inferred from homology;
KW   Cell projection {ECO:0000256|ARBA:ARBA00022846};
KW   Cilium {ECO:0000256|ARBA:ARBA00022846};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   REGION          488..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..535
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   569 AA;  65174 MW;  49DE6EDF9F930D04 CRC64;
     MNRLYDMEPR VMDDEMLKLA VGEQGPRDEA RQLAKQEGIL FKDVLSLQLD FQNILRIDNL
     WQFENLRKLQ LDNNIIEKIE GLENLTRLVW LDLSFNNIEA IEGLDTLVNL EDLSLFNNRI
     SKIDSLDALV KLQVLSLGNN QIGNMMNIIY LRRFKDLRTL SLSGNPVAEA EDYRTFICAY
     LPDLVYLDFR RIDDHTKELA EMKHQCSVDE LKHQESLMQA QLEDEQARWE ELEGHKAAFV
     EHLNGPFLFD SMYAEDVEGS QLSHLPGVGE LVQTYKDKFV IVCLNIFESG LKQQEKRKAE
     LDTFMGCVQE AIQEKQEQGK HKIAKFEEKH LLTLSSIRDE SELTNFEKKM AEHSEDITEL
     VNVLVTLEMQ LVEQLEETIN MFERNIIDLV GLFVENVQSL MAQCRDLENH HHEKLLEIAI
     STREKIVKGE LDEDLPDAVR PLFVDKDTIV NAVGASHDIH LLKIDNREDE LVTRVNSWCA
     HLVDKVSAAE GREERSQEGR LRIPPDGPAA VCPADSQGRD HEEPQAREGD QPVRRPCAER
     AGQPGVQRPP GLGLWPSPPP DPRTSQVEK
//