ID A0A2Y9M6W8_DELLE Unreviewed; 295 AA.
AC A0A2Y9M6W8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Deleted in azoospermia-like {ECO:0000313|RefSeq:XP_022417465.1};
GN Name=DAZL {ECO:0000313|RefSeq:XP_022417465.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022417465.1};
RN [1] {ECO:0000313|RefSeq:XP_022417465.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022417465.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_022417465.1; XM_022561757.1.
DR AlphaFoldDB; A0A2Y9M6W8; -.
DR STRING; 9749.A0A2Y9M6W8; -.
DR KEGG; dle:111168168; -.
DR InParanoid; A0A2Y9M6W8; -.
DR OrthoDB; 3964771at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd12672; RRM_DAZL; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR043628; DAZ_dom.
DR InterPro; IPR037551; DAZ_RRM_vert.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR11176; BOULE-RELATED; 1.
DR PANTHER; PTHR11176:SF4; DELETED IN AZOOSPERMIA-LIKE; 1.
DR Pfam; PF18872; Daz; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS51890; DAZ; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 40..115
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 167..190
FT /note="DAZ"
FT /evidence="ECO:0000259|PROSITE:PS51890"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 295 AA; 33033 MW; ACE64F5AF5FAC8AE CRC64;
MSAADPDTPN STISREASTQ SSSAATSQGY VLPEGRIMPN TVFVGGIDVR MDETEIKNFF
AKYGSVKEVK IITDRSGVSK GYGFVSFYND VDVQKIVESQ INFHGKKLKL GPAIRKQTLC
AYHVQPRPLV FNPPPPPQFQ SVWSNPHTEA YMQPPTMMSP ITQYVQAYPP YPSSPVQVIT
GYQLPVYNYQ MPPQWPVGEQ RSYVISPTYT AVNYHCNEVD PGVEVLPSEC SVHEATASSG
NGPQKKSVDR SIQTVVSCLF NPENRLRSSF VTQEEYFKDK RVHHFRRSRA VLKSV
//
