ID A0A2Y9M995_DELLE Unreviewed; 303 AA.
AC A0A2Y9M995;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Protein lin-7 homolog A isoform X1 {ECO:0000313|RefSeq:XP_022415652.1};
GN Name=LIN7A {ECO:0000313|RefSeq:XP_022415652.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022415652.1};
RN [1] {ECO:0000313|RefSeq:XP_022415652.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022415652.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004202}.
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DR RefSeq; XP_022415652.1; XM_022559944.2.
DR AlphaFoldDB; A0A2Y9M995; -.
DR STRING; 9749.A0A2Y9M995; -.
DR Ensembl; ENSDLET00000009002; ENSDLEP00000008137; ENSDLEG00000005973.
DR KEGG; dle:111167272; -.
DR InParanoid; A0A2Y9M995; -.
DR OrthoDB; 4175920at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR14063; PROTEIN LIN-7 HOMOLOG; 1.
DR PANTHER; PTHR14063:SF4; PROTEIN LIN-7 HOMOLOG A; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 95..150
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 178..260
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 263..299
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 33..53
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 33387 MW; CCA0E8702CD1EA13 CRC64;
MLSLSGTCSA SRRIRRSAPR GTVASPSGCQ PTQAFSPPQP PPSLLPPSFP SSLSTPPPIS
SSFSHYKRLL MLKLSVTSAP TADMATLTVV QPLTLDRDVA RAIELLEKLQ ESGEVPVHKL
QSLKKVLQSE FCTAIREVYQ YMHETITVNG CPEFRARATA KATVAAFAAS EGHSHPRVVE
LPKTDEGLGF NVMGGKEQNS PIYISRIIPG GVAERHGGLK RGDQLLSVNG VSVEGEHHEK
AVELLKAAKD SVKLVVRYTP KVLEEMEARF EKLRTARRRQ QQQLLIQQQQ QQRQQQTQQN
HMS
//
