ID   A0A2Y9MAT8_DELLE        Unreviewed;       485 AA.
AC   A0A2Y9MAT8;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 1 isoform X7 {ECO:0000313|RefSeq:XP_022418835.1};
GN   Name=APBB1 {ECO:0000313|RefSeq:XP_022418835.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022418835.1};
RN   [1] {ECO:0000313|RefSeq:XP_022418835.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022418835.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_022418835.1; XM_022563127.2.
DR   AlphaFoldDB; A0A2Y9MAT8; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR   CDD; cd01272; PTB1_Fe65; 1.
DR   CDD; cd01271; PTB2_Fe65; 1.
DR   CDD; cd00201; WW; 1.
DR   Gene3D; 2.20.70.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039576; APBB1/2/3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR001202; WW_dom.
DR   InterPro; IPR036020; WW_dom_sf.
DR   PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR   PANTHER; PTHR14058:SF5; AMYLOID BETA PRECURSOR PROTEIN BINDING FAMILY B MEMBER 1; 1.
DR   Pfam; PF00640; PID; 2.
DR   Pfam; PF00397; WW; 1.
DR   SMART; SM00462; PTB; 2.
DR   SMART; SM00456; WW; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF51045; WW domain; 1.
DR   PROSITE; PS01179; PID; 2.
DR   PROSITE; PS01159; WW_DOMAIN_1; 1.
DR   PROSITE; PS50020; WW_DOMAIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   DOMAIN          30..62
FT                   /note="WW"
FT                   /evidence="ECO:0000259|PROSITE:PS50020"
FT   DOMAIN          147..284
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          317..474
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          52..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          89..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..108
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   485 AA;  53657 MW;  ADDEBBE603C61DFF CRC64;
     MFSQDFFLAI VLQDSSPDSF WNPNAFETDS DLPAGWMRVQ DTSGTYYWHI PTGTTQWEPP
     GQASPSQGSS PREESQLTWT GFTHGEGFED GEFWKDEPSE EAPMDLGLKD PEEGTLPFPA
     QSLSPEPLPQ EEEKLPPRNA NPGIKCFAVR SLGWVEMTEE ELAPGRSSVA VNNCIRQLSY
     HKNNLHDPMS GGWGEGKDLL LQLEDETLKL VEPHSQALLH TQPIVSIRVW GVGRDSGRDF
     AYVARDKLTQ MLKCHVFRCE APAKNIATSL HEICSKIMAE RRNARCLVNG LSLDHSKLVD
     VPFQVEFPAP KNELVQKFQV YYLGNVPVAK PVGVDVINGA LESVLSSSSR EQWTPSHVSV
     APATLTILHQ QTEAVLGECR VRFLSFLAVG RDVHTFAFIM AAGPASFCCH MFWCEPNAAS
     LSEAVQAACM LRYQKCLDAR SQASTSCLPA PPAESVARRV GWTVRRGVQS LWGSLKPKRL
     GAHTP
//