ID   A0A2Y9MBH9_DELLE        Unreviewed;       555 AA.
AC   A0A2Y9MBH9;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Dynein regulatory complex subunit 3 {ECO:0000256|ARBA:ARBA00040950};
GN   Name=DRC3 {ECO:0000313|RefSeq:XP_022416452.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022416452.1};
RN   [1] {ECO:0000313|RefSeq:XP_022416452.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022416452.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC       {ECO:0000256|ARBA:ARBA00004611}.
CC   -!- SIMILARITY: Belongs to the DRC3 family.
CC       {ECO:0000256|ARBA:ARBA00038378}.
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DR   RefSeq; XP_022416452.1; XM_022560744.2.
DR   AlphaFoldDB; A0A2Y9MBH9; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973:SF12; DYNEIN REGULATORY COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF14580; LRR_9; 1.
DR   SMART; SM00365; LRR_SD22; 3.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   3: Inferred from homology;
KW   Cell projection {ECO:0000256|ARBA:ARBA00022846};
KW   Cilium {ECO:0000256|ARBA:ARBA00022846};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   REGION          474..555
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..521
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   555 AA;  63687 MW;  EEEC93A128699E63 CRC64;
     MNRLYDMEPR VMDDEMLKLA VGEQGPRDEA RQLAKQEGIL FKDVLSLQLD FQNILRIDNL
     WQFENLRKLQ LDNNIIEKIE GLENLTRLVW LDLSFNNIEA IEGLDTLVNL EDLSLFNNRI
     SKIDSLDALV KLQIIYLRRF KDLRTLSLSG NPVAEAEDYR TFICAYLPDL VYLDFRRIDD
     HTKELAEMKH QCSVDELKHQ ESLMQAQLED EQARWEELEG HKAAFVEHLN GPFLFDSMYA
     EDVEGSQLSH LPGVGELVQT YKDKFVIVCL NIFESGLKQQ EKRKAELDTF MGCVQEAIQE
     KQEQGKHKIA KFEEKHLLTL SSIRDESELT NFEKKMAEHS EDITELVNVL VTLEMQLVEQ
     LEETINMFER NIIDLVGLFV ENVQSLMAQC RDLENHHHEK LLEIAISTRE KIVKGELDED
     LPDAVRPLFV DKDTIVNAVG ASHDIHLLKI DNREDELVTR VNSWCAHLVD KVSAAEGREE
     RSQEGRLRIP PDGPAAVCPA DSQGRDHEEP QAREGDQPVR RPCAERAGQP GVQRPPGLGL
     WPSPPPDPRT SQVEK
//