ID A0A2Y9MBK2_DELLE Unreviewed; 976 AA.
AC A0A2Y9MBK2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=RE1-silencing transcription factor-like isoform X2 {ECO:0000313|RefSeq:XP_022419086.1, ECO:0000313|RefSeq:XP_022419095.1};
GN Name=LOC111169295 {ECO:0000313|RefSeq:XP_022419086.1,
GN ECO:0000313|RefSeq:XP_022419095.1, ECO:0000313|RefSeq:XP_022419105.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022419105.1};
RN [1] {ECO:0000313|RefSeq:XP_022419086.1, ECO:0000313|RefSeq:XP_022419095.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022419086.1,
RC ECO:0000313|RefSeq:XP_022419095.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022419086.1; XM_022563378.2.
DR RefSeq; XP_022419095.1; XM_022563387.2.
DR RefSeq; XP_022419105.1; XM_022563397.2.
DR Ensembl; ENSDLET00000021030; ENSDLEP00000019082; ENSDLEG00000013880.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24403:SF102; RE1-SILENCING TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR24403; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 158..185
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 275..302
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 303..330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 331..359
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 360..387
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 939..961
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 82..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..593
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..635
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..666
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..707
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..811
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..841
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 884..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 108036 MW; EB8EE7EADD0F120B CRC64;
MATQVMGQSS GGGGLFTGSG TMGMALPNDM YDLPDLSRAE LAAPQLIMLA NVALTGEVNG
GCCDYLVGEE RQMAELMPVG DNNFSDSDGE GLEESPEVKG EPSALENMEL ESLELSVVQP
RPVFEVSAAS EPYSANKDLP RETPVAEDKC KNLKTKPFRC KPCQYEAESE EQFVHHIRVH
SAKKFFVEES AEKQAKAREC GSSTGEEGDF SKGPIRCDRC GYNTNRYDHY TAHLKHHTRA
GDNERVYKCI ICTYTTVSEY HWRKHLRNHF PRKVYTCGKC NYFSDRKNNY VQHVRTHTGE
RPYKCELCPY SSSQKTHLTR HMRTHSGEKP FKCDQCSYVA SNQHEVTRHA RQVHNGPKPL
NCPHCDYKTA DRSNFKKHVE LHVNPRQFNC PVCDYAASKK CNLQYHFKSK HPTCPNKTMD
VSKVKLKKTK KREADLPDNK ITNEKTETEQ TKMKGDVTGK KNERSVKVEK KDNVSKEKKP
CSNAASQVTT RTRKSALEAK EMDVHPGNNA EKSCKSKKSK RKTEAEARSL QEPVNDEEPV
TKKKKKAESK SRNSQEVLKG DSKVEENKKQ SICMKNSAKK KTLRSKSCKK SGKPAQRRAT
QIEPPPPMES AEGGPVQTEP PPAAPPSPPP PLAPEWHAEV EVVQAEPPPP PPLPPPSPPP
PLPPGGHAEV EVVQKGPVHA EPPPPVEPIP KRSPHKDNGK EKSNMQSEMV QKEQVLIEVG
LVPVKDRQLL KESAGAQDLL PPSPPLPKED LKEEESEDQK LVPAGEGHKE APLQKVEAEE
ADKSLAGLAA VTKASASISS SEQNLTMPEG ETSDGKHQAD AMLCEMKMDA DEKKTENPPG
RDSVVEEPAS PPLLPLPLEK CEAVSTATVA SPPVTVAVNE SQEMDEDEGI HSHDGSDLSD
NMSEDSDDSG LNGARPVPQE TSRKNGKEAL AVKVAEGDFV CIFCDRSFRK EKDYSKHLNR
HLVNVYFLEE AAQGQE
//
