ID A0A2Y9MP10_DELLE Unreviewed; 607 AA.
AC A0A2Y9MP10;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Autophagy-related protein 16-1 isoform X1 {ECO:0000313|RefSeq:XP_022423700.1};
GN Name=ATG16L1 {ECO:0000313|RefSeq:XP_022423700.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022423700.1};
RN [1] {ECO:0000313|RefSeq:XP_022423700.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022423700.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC {ECO:0000256|ARBA:ARBA00009271}.
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DR RefSeq; XP_022423700.1; XM_022567992.2.
DR AlphaFoldDB; A0A2Y9MP10; -.
DR STRING; 9749.A0A2Y9MP10; -.
DR Ensembl; ENSDLET00000015657; ENSDLEP00000014189; ENSDLEG00000010427.
DR KEGG; dle:111171948; -.
DR InParanoid; A0A2Y9MP10; -.
DR OrthoDB; 458014at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR CDD; cd22887; Atg16_CCD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR045160; ATG16.
DR InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR Pfam; PF08614; ATG16; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 16..206
FT /note="Autophagy-related protein 16"
FT /evidence="ECO:0000259|Pfam:PF08614"
FT REPEAT 318..351
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 362..403
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 404..445
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 462..484
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 540..571
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 573..607
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 82..230
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 607 AA; 68223 MW; CF738EB8E6B3FFFF CRC64;
MSSGLRASVF PRWKRHISEE LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAHKLQAEK
HDIPNRHEIS PGHDGAWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQQK
DKEMQMNEAK IAECLQTISD LETECLELRT KLQDLERANQ TLKDEYDALQ ITFTALEEKL
RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPAEQDDDI
EVLVDETSDH AEEASPVRAV SRAAAKRLSQ PAGGLLDSIT NIFGRRSVSS FPVPQDNVDT
HPGSSKEVRV PTTAMCVFDA HDGEVNAVQF SPGSRLLATG GMDRRVKLWE VFGDKCEFKG
SLSGSNAGIT SIEFDSAGSY LLAASNDFAS RIWTVDDYRL RHTLTGHSGK VLSAKFLLDN
ARIVSGSHDR TLKLWDLRSK VCIKTVFAGS SCNDIVCTEQ CVMSGHFDKK IRFWDIRSES
IVREMELLGK ITALDLNPER TELLSCSRDD LLKIIDLRIN AVRQTFSAPG FKCGSDWTRV
VFSPDGSYVA AGSAEGSLYI WSVLSGKVEK VLSKHHSSAI NAVAWSPAGS HVVSVDKGSK
AVLWSEY
//
