ID A0A2Y9MX44_DELLE Unreviewed; 849 AA.
AC A0A2Y9MX44;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Plakophilin-4 isoform X13 {ECO:0000313|RefSeq:XP_022425506.1};
GN Name=PKP4 {ECO:0000313|RefSeq:XP_022425506.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022425506.1};
RN [1] {ECO:0000313|RefSeq:XP_022425506.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022425506.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR RefSeq; XP_022425506.1; XM_022569798.2.
DR AlphaFoldDB; A0A2Y9MX44; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF8; PLAKOPHILIN-4; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 4.
DR SMART; SM00185; ARM; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT REPEAT 227..254
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 271..314
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 529..566
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 39..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 849 AA; 95330 MW; D80922B9A42AD9B7 CRC64;
MTAVPQHLGP SLQRTVHDME QFGQQQYDIY ERMVPPRPDS LTGLRSSYAS QHSQLGQDLR
STVSPDLHIT PIYEGRTYYS PVYRSPNHGT VELQGSQTAL YRTGSGVGNL QRTSSQRSTL
TYQRNNYALN TTATYAEPYR PIQYRVQECN YNRLQHIAPA EDGTTRSPSI DSIQKDPREF
AWRDPELPEV IHMLQHQFPS VQANAAAYLQ HLCFGDNKVK LEVCRLGGIK HLVDLLDHRV
LEVQKNACGA LRNLVFGKST DENKIAMKNV GGIPALLRLL RKSVDAEVRE LVTGVLWNLS
SCDAVKMAII RDALSTLTNT VIVPHSGWNN SSFDDDHKIK FQTSLVLRNT TGCLRNLSSA
GEEARRQMRS CEGLVDSLLY VIHTCVNTSD YDSKTVENCV CTLRNLSYRL ELEVPQARPL
GLNELDDLLG KESPSKDLEP SCWGKKKKKK KRTPQEDQWD GVGPIPGLSK SPKGVEMLWH
PSVVKPYLNL LAESSNPATL EGSAGSLQNL SAGNWKFAAY IRAAVRKEKG LPILVELLRM
DNDRVVSSVA TALRNMALDV RNKELIGKYA MRDLVNRLPG GTSPSVLSDE TVAAICCALH
EVTSKNMENA KALADSGGIE KLVNITKGRG DRSSLKVVKA AAQVLNTLWQ YRDLRSIYKK
DGWNQNHFIT PVSTLERDRF KSHPSLSTTN QQMSPVIQSV GSTSSSPALL GIRDPRSEYD
RTQPPMQYYS SQGDATHRGL YPGSSKPSPI YISSYSSPAR EQNRRLQHQQ LYYSQDDSNR
KNFDAYRLYL QSPHSYEDPY FDDRVHFPAS TDYSTQYGLK STTNYVDFYS TKRPSYRSEQ
YPGSPDSWV
//
