ID A0A2Y9MZH2_DELLE Unreviewed; 453 AA.
AC A0A2Y9MZH2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Actin-like protein 7A {ECO:0000256|ARBA:ARBA00016971};
GN Name=LOC111171178 {ECO:0000313|RefSeq:XP_022422513.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022422513.1};
RN [1] {ECO:0000313|RefSeq:XP_022422513.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022422513.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play an important role in formation and fusion of Golgi-
CC derived vesicles during acrosome biogenesis.
CC {ECO:0000256|ARBA:ARBA00029378}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the actin family.
CC {ECO:0000256|ARBA:ARBA00006752, ECO:0000256|RuleBase:RU000487}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022422513.1; XM_022566805.1.
DR AlphaFoldDB; A0A2Y9MZH2; -.
DR STRING; 9749.A0A2Y9MZH2; -.
DR KEGG; dle:111171178; -.
DR InParanoid; A0A2Y9MZH2; -.
DR OrthoDB; 5294390at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR031769; ACTL7A_N.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF167; ACTIN-LIKE PROTEIN 7A; 1.
DR Pfam; PF00022; Actin; 1.
DR Pfam; PF16840; ACTL7A_N; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Fertilization {ECO:0000256|ARBA:ARBA00023279};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 19..83
FT /note="Actin-like protein 7A N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16840"
FT REGION 57..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_022422513.1"
SQ SEQUENCE 453 AA; 51200 MW; 96C760A6C15E114A CRC64;
LEASGIEELS ESKTALESVW APQAAIIGDW PSERTGEQDS LQTRVLQTAS LKDGPAKQAV
WVRRNRSEPE EPTKSPVVNE KPKLELTKAV VVDLGTGYCK CGFAGLPKPT HMISPTVGKP
YMETAKTGDS HKETFVWHEL INPEVCLKLI NLLRHGIIMD WDTVQAIWEY LFHQEMKIAP
EEHAALVSDP PLSPHTNRQK YAEMLFETFK TPAMHIAYQS RLSVYSYRRT SGLVVEVGHG
VSYVVPIYEG YPLPNITGRL DYAGSDLTTY LMGLMNNSGK HFTEDQLGIV EDIKKKCCFV
ALVPTEEKKV PATEHTIQYT LPDGQEIYLC QERFLCSEMF FKPSLIKSMQ LGLHTQTVSC
LNKCDITLKR DLMGYILLCV GSTMLSGFPN HRQKELRSMC PNDTPQVNML PERDTAVWTG
GSLLASLQGF QPLWVHCFEY EEHGPFFLYR RCF
//
