ID A0A2Y9N6L6_DELLE Unreviewed; 1006 AA.
AC A0A2Y9N6L6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=StAR-related lipid transfer protein 13 isoform X4 {ECO:0000313|RefSeq:XP_022430349.1};
GN Name=STARD13 {ECO:0000313|RefSeq:XP_022430349.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022430349.1};
RN [1] {ECO:0000313|RefSeq:XP_022430349.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022430349.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022430349.1; XM_022574641.1.
DR AlphaFoldDB; A0A2Y9N6L6; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04375; RhoGAP_DLC1; 1.
DR CDD; cd08909; START_STARD13-like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 6.10.250.1870; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR12659:SF6; STAR-RELATED LIPID TRANSFER PROTEIN 13; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 556..761
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 807..975
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT REGION 44..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 111510 MW; 9FFEBE27CF7AEE9C CRC64;
MRVILDVSQG DDSDEEDLCI SHKWTFQRTS RRWSRVDDLH AVFPGGDRNG SSGDITMRNT
TSSESVLTDL SEPEVCSIHS ESSGGSDGRS QPGSYGAGRE ALDGPGQYCA HGPAMLDATL
GGSSLPPSPR DGLQHPLHPK NEKPSRARAK SFLKRMETLR GKGAQGRQKG SGRTGGLVIS
GPVLQQEPES FKAMQCIQIP NGDLQNSTPA ACKTGLPGPS KWSGESSPSE NSSSGVSTPG
LKERRCQEAH KRGGMYLEDL DVLAGTALRG AGDQNHAREF HSQENLVVHI PKDHKPGTFP
KALSIESLSP TDNSSAVNWR TGNVSPGRRP GPGAGEPRLM ASCHRASRVS IYDNVPGSHL
YASTGDLLDL EKDDLFPHLD DILHHVNGLQ EVVDDWSKNL LPELQTHNAL SGEAGFCPFP
PPSQITLDFE GNSVSEGRTT PSDVERDGAS LNESEAAGVR ERRDSGVGAS LTRPNRRLRW
NSFQLSHQPQ PSTASPHISG QTAGQLNLLQ RFSLLRLTAI MEKHSMSNKH GWTWAVPKFM
KRMKVPDYRD KTVFGIPLIV HVQRTGQPLP QSIQQALRYL RSNCLDQVGL FRKSGVKSRI
HALRQMNESF PENVSYEDQS AYDVADMVKQ FFRDLPEPLF TNKLSETFLH IYQYVPKEQQ
LQAVQAAVLL LADESREVLQ TLLCFLNDVV HAVEENQMTP MNLAVCLAPS LFHLNLLKKE
SSPRVIQKKY ASGKPDQKDL SENLAAAQGL AHMIMECDRL FEVPLEMVAQ SHNSYMEAEI
HPPTLEDLGA QLEESGATFH TYLEHLIQGL QKEAKEKFKG WVTCSNTDNT ELAFKKVGDR
HPLKLWKASV EVEAPPSVVL NRVLRERHLW DEDFVQWKVV ETLDKQTEIY QYVQNSMAPH
PSRDFLVLRT WKTDLPKGMC TLVSLSVDHE EAQLMGGVRA VVMDSQYLME PCGSGKSRLT
HICRVDLRGH SPEWYNKGFG HLCAAEVARI RNSFQPLIAE GPETKI
//
