ID A0A2Y9N8H7_DELLE Unreviewed; 1874 AA.
AC A0A2Y9N8H7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Lymphocyte antigen 75 isoform X4 {ECO:0000313|RefSeq:XP_022425543.1};
GN Name=LOC111172783 {ECO:0000313|RefSeq:XP_022425543.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022425543.1};
RN [1] {ECO:0000313|RefSeq:XP_022425543.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022425543.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR RefSeq; XP_022425543.1; XM_022569835.2.
DR STRING; 9749.A0A2Y9N8H7; -.
DR InParanoid; A0A2Y9N8H7; -.
DR OrthoDB; 4271106at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 11.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 11.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF65; LYMPHOCYTE ANTIGEN 75; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 10.
DR SMART; SM00034; CLECT; 11.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 11.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 10.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1874
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015894988"
FT TRANSMEM 1811..1835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 164..211
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 225..341
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 369..487
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 508..615
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 653..764
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 959..1083
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1111..1213
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1252..1360
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1402..1504
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1543..1653
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1674..1786
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 1874 AA; 215561 MW; 515647ECC797AB62 CRC64;
MRTRWSTPLR AAELLVLLLP CFGLVEPSGR SGGDSFTIVN ENTGKCITPL NDWIVAKDCD
ETKDMLWKWV SQHRLFHLQS QKCLGLDITK PVDSLRMFSC DSNAMLWWKC EHRSLYGAAR
YRLTLKGGHA IASTNSSDVW KKGGSEENLC AQPYHEIYTR DGNSYGRPCE FPFLVNGTWH
HECIHDGDHS GPWCATTLNY EYDQKWGICL QPENGCEDYW EKKEEMGSCY QFNTQATLSW
KKAYVSCQNQ GADLLSINSA AELTYLTEKE GIPRIFWIGL NQLYSARGWE WSDHKPLNFL
NWDPDVPSAP VIGRSSCARM DADSGLWQSF SCEAQLPYVC KKLLNNTVEL TDVWTYSDTR
CDAADWLPNN GFCYLLVNES DSWDKAHMKC KTFSSDLISI HSLADVELIV TKLHNGDAKE
EIWTGLRNIN TPTLFQWSDG TEVTLTYWDE NEPHVPYNKT PNCVSYLGKL GQWKVQSCEE
KLKYVCKKKG EKLNDTRSDK MCPPVEGWKR HGEACYKIYK DEVPFGTNCN LTVTSRFEQE
YLNDMIKKYT KSPEKYFWTG LRDTDASGEY SWGSAGGIKR AVTFSNWNFL EPASPGGCVA
MATGKSLGKW EVKDCRSFRA LSICKKISER PEPEKAAPKP EDPCPEGWHS SPSGLSCYKL
FHIERIVRKR NWEEAERFCQ ALGGHLPSFS HMDEIKKFLH FLTDQFSDQR WLWIGLNKRS
PDLQGSWQWS DHTPVSTIIT ANEFQQDYDI RDCAAVKVIN RPWRRRWYFY DDREFMYLRP
FACDTKLEWM CQIPKGRTPK MPDWYNPERA GIHGPPVVIE GSEYWFVADP RLNYEEAVLY
CASNHSSLAS LTSFAGLRAI KNKIANISGN EEKWWVRTTD QLLERRFLSS RHPFHHFPIT
FGEECFYLSA KTWFSDINKP ADCSTKLPFV CEKYNVSSLE KYSPDSAAKI QCSGDWITFQ
NKCFLRIKPK SVTFSEASDT CHTYGGTLPS VLSQREQDFI TSLLPDMEAT LWIGLRWTAY
EKINKWMDNR ELTYSNFHPL LVGRRLRIPT NIFDEEVSYH CALMLNLQKS PFTGTWNFTS
CSEHHTLSLC QKYSEIESRQ TLQNTSETVK YQNNLYKIML KTLTWTDALK ECQKENMQLV
SITDPYQQAF LTVQAVLHNT SLWIGLSSHD DELNFGWSDG KHLQFNRWAE NNEQLEDCVV
LDTDGFWKTS DCDNNQPGAI CYYSGNETEK EVKPVTSVRC PSPVLNTPWI PFQNSCYNFM
ITKNRYIVTT RDEVHSKCQT LNPKSHILSI RDEKENNFVL EQLLHYNYMA SWVMLGITYE
NNSLMWSDKT TLSYTHWRSG RPAVQNGKFF AGLNTDGFWD IQTFNVVEDI LYFHQHSILA
CKIEMVDYKE DCNTTLPRFI PHEDGIYNVI QKRVTWYEAL NTCSQSGGHL ASVHDQNGQL
FLEDIVKRDG FPLWVGLSSH DGSESSFEWS DGSAFDYIPW KDKKSAGNCV VLDPKGIWKH
EKCNSVKDGA ICYKPTKSKE VSSHTYSSRC PAVKGNESQW IQYRDHCYTS DQALHSFSEA
RRFCSELDHS ATIVTIKDED ENKFVSRLIR ENNNITMRVW LGLSQLSADQ SWNWLDGSKV
TFVKWANKFK SGSGQCSILL ASNETWIKVE CSRGYGRVVC RVPLDCPSST WVQFQDSCYI
FLQEAIKVES IEDVRNQCTD HGADMISIHN EEENAFILDT LQKQWKGPDD ILLGMFFDTD
DDSFKWFDKS NMTFVKWSDQ EDGEDLVDTC AFLHTKTGDW KKGNCEVSSV EGTLCKAAIP
YEKKYLSDNH ILISALVIAS TVILTVLGAV VWFLYKRSLD SGFTTVFSAA PQSPYNDDCV
LVVAEENEYD VQFD
//
