ID A0A2Y9NCK1_DELLE Unreviewed; 590 AA.
AC A0A2Y9NCK1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=ETS-related transcription factor Elf-1 isoform X2 {ECO:0000313|RefSeq:XP_022430656.1};
GN Name=ELF1 {ECO:0000313|RefSeq:XP_022430656.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022430656.1};
RN [1] {ECO:0000313|RefSeq:XP_022430656.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022430656.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022430656.1; XM_022574948.2.
DR AlphaFoldDB; A0A2Y9NCK1; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR022084; TF_Elf_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF156; ETS-RELATED TRANSCRIPTION FACTOR ELF-1; 1.
DR Pfam; PF12310; Elf-1_N; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 184..266
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 134..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 64268 MW; 15FD404111D4FBF5 CRC64;
MAAVVQQNDL VFEFASNVME DEQQLGDPAI FPAVIVEHVP GADILNSYAG LACVEEPNDM
ITESSLDVAE EEIIDEDDDD ITLTVEASCH NGDETIETIE AAEALLNMDS PGPMLDEKRI
NGIPEVMETQ HVQETYAHSP GRSSPEQPKR KKGRKTKPPR PDSPATTPNI SVRKKNKDGK
GNTIYLWEFL LALLQDKATC PKYIKWTQRE KGIFKLVDSK AVSRLWGKHK NKPDMNYETM
GRALRYYYQR GILAKVEGQR LVYQFKDMPK DLIYIDDEDP SSSIESSDPS LSSTTTSSRN
QASRSRVSSG PGIKGGATTV LKPGNSKAAK PKDPVEPAQP SEVLRTMQST QTPYPTQLFR
TIHVVQPVQA VPEGEATSSM QDETLNSSVQ SIRTIQAPAQ VPVVVSPGNQ HLHTVTLQTV
PITTVIASTD PSSGAGSQKF ILQAIPSSQP VTVLKENVVL QSQKPGSPPS IVLSPAHVQQ
VLTSNVQSIC NGTVSVASSP SFSATTPVVT FSPRSSQLVT HPPGTVITSV IKAQETKTHI
QEVEKKEVED KLKEGTGETE QHSQPYVMVV SNGFTSQVAI KNELLEPNSF
//
