ID A0A2Y9NF21_DELLE Unreviewed; 1837 AA.
AC A0A2Y9NF21;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=InaD-like protein isoform X5 {ECO:0000313|RefSeq:XP_022431546.1};
GN Name=PATJ {ECO:0000313|RefSeq:XP_022431546.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022431546.1};
RN [1] {ECO:0000313|RefSeq:XP_022431546.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022431546.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004202}.
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DR RefSeq; XP_022431546.1; XM_022575838.1.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 11.
DR Gene3D; 1.20.1440.360; -; 1.
DR Gene3D; 2.30.42.10; -; 11.
DR InterPro; IPR015132; L27_2.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF44; PATJ HOMOLOG; 1.
DR Pfam; PF09045; L27_2; 1.
DR Pfam; PF00595; PDZ; 11.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 11.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 11.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 11.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 5..65
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 134..221
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 248..328
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 366..454
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 553..639
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 686..758
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1069..1132
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1177..1260
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1395..1478
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1491..1573
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1631..1717
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1754..1837
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 453..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1115..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1269..1295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1578..1597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1837 AA; 199507 MW; 6B3D4151C83900A9 CRC64;
MPENPATDKL QVLQVLDRLK IKLQEKGDTS QNEKLSMFYE TLKSPLFNQI LTLQQSIKQL
KGQLSHLPSD CSANFDFSRK GLLVFTDGAI TNGNAHRSSN NLTVSGLFPW TPVLGNEDFN
SIMQQMAQGR QVEYIDIERP STGGLGFSVV AFRGQNLGEV DIFVKEVQPG SIASRDQRLK
ENDQILAINH TPLDQNISHQ QAIALLQQTT GSLHLVVARE PVHTKSSTST SLTDASLPET
VSWGHIEDVE LINDGSGLGF GIVGGKSSGV VVRTIVPGGL ADRDGRLQTG DHILKIGSTN
VQGMTSEQVA QVLRNCGNSV RMLVARDPVG EISIAPPTPA ALPVALPAVA NRSPSSDSST
LFETYDVELI KKDGQSLGIR IVGYVGTAQT GEASGIYVKS IIPGSAAYHN GQIQVNDQIV
AVDGVNIQGF ANQDVVEVLR NAGQVVHLTL VRRKTSSSAS PHEGPSDRGT VVEPPKTPAL
FLTGAVEKET NFGEDEETEE RMDNLKNDNL QALEKLEGVP ASLENELKSR WENLLGPDYE
VMIATLDTQI ADDAELQKYS KLLPIHTLRL GMEVDSFDGH HYISSIAPGG PLDTLNLLQP
EDELLEVNGV QLYGKSRREA VSFLKEVPPP FTLVCCRRLF DDEASVDEPR TTETSLPEME
ADHNTDVSPE EDDDGELALW SPEVKIVELV KDHKGLGFSI LDYQDPLDPT RSVIVIRSLV
ADGVAERGRE LLPGDRLVSV NEYCLDNTTL AEAVEVLKAV PPGIVHLGIC KPLVEGDKEE
ENHILHSNNN EDKTDISGTV HDINSSLILE APKGFRDEPY FKEELVDEPF LDLGKAFQSQ
QKEIDNSKEA WEMLEFMAPR LQEMGEEREM LVDEEYELYQ NHFQSMELYP SSHIQEAAHV
PSTKELHFGT QWYQDCELPE PQEARSMMSV YSQEMQQCGY STEKMMKENF GIDSLSSIPS
TEGNSQQSRF DDLENLNSLT KSSLDLGMMI PNDVQGPGLL VELPAVAQTR EQEDLPLYQL
PRALAVSKAS AYIGMLSSRH ATDACELPER EEGEGEETPN FSHWGPPRIV EIFREPDVSL
GISIVGGQTV IKRLKNGEEL KGIFIKQVLE DSPAGKTNAL KTGDKILERR GTAPPPMKLP
PPYKAPSDDS DETEEEYALT NKKIRQRYAD LPGELHIIEL EKDKNGLGLS LAGNKDRSRM
SIFVVGINPE GPAATDGRMR IGDELLEINN QILYGRSHQN ASAIIKTAPS KVKLVFIRNE
DAVSQMAVTP FPLPSSSPSS TEDQSGTSEE DSSLEACIKQ LPKSESSKLE DISQVVGQGV
VAGQQKALEC PTDSAGSQMK QQKYSTKVSF SSQEIPLAPS SYHSADADFT GYGGFHAPMS
VDPATCPIVP GQEMIIEISK GRSGLGLSIV GGKDTPLDAI VIHEVYEEGA AARDGRLWAG
DQILEVNGID LRSASHEEAI TALRQTPQKV RLVVYRDEAY YRDEENLEVF PVDLQKKAGR
GLGLSIVGKR NGSGVFISDI VKGGAADLDG RLIQGDQILS VNGEDMRSAS QETVATILKC
AQGLVQLEIG RLRAGSWTSS RKTSQSSQQS QHSSLHPSLA PVITSLQNLV GTKRALDPSP
KNSGTDVGLR TIEIIRELSD ALGISIAGGK GSPLGDIPIF IAMIQASGVA ARTQKLKVGD
RIVSINGQPL DGLSHADVVN LLKNAYGRII LQVVADTNIS GMATQLENMS TGYPLGSPAA
KHHPEDTETP PPKIITLEKG SEGLGFSIVG GYGSPHGDLP IYVKTIFAKG AAADDGRLKR
GDQILAVNGE TLEGVTHEEA VAILKHQRGT VVLTVLS
//
