ID   A0A2Y9NFS2_DELLE        Unreviewed;      1120 AA.
AC   A0A2Y9NFS2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=ELKS/Rab6-interacting/CAST family member 1 isoform X2 {ECO:0000313|RefSeq:XP_022432895.1};
GN   Name=ERC1 {ECO:0000313|RefSeq:XP_022432895.1};
OS   Delphinapterus leucas (Beluga whale).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Monodontidae; Delphinapterus.
OX   NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022432895.1};
RN   [1] {ECO:0000313|RefSeq:XP_022432895.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022432895.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   RefSeq; XP_022432895.1; XM_022577187.1.
DR   AlphaFoldDB; A0A2Y9NFS2; -.
DR   Proteomes; UP000248483; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:UniProt.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 1.20.5.2440; -; 1.
DR   Gene3D; 1.20.5.340; -; 1.
DR   InterPro; IPR019323; ELKS/CAST.
DR   InterPro; IPR037245; FIP-RBD_C_sf.
DR   InterPro; IPR019018; Rab-bd_FIP-RBD.
DR   PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR   PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR   Pfam; PF10174; Cast; 2.
DR   Pfam; PF09457; RBD-FIP; 1.
DR   SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS51511; FIP_RBD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT   DOMAIN          1050..1112
FT                   /note="FIP-RBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51511"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          589..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          788..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          151..178
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          215..249
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1066..1093
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        31..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1120 AA;  128327 MW;  0C438CBDA777500E CRC64;
     MYGSARSVGK VEPSNQSPGR SPRLPRSPRL GHRRTNSTGG SSGSSVGGGS GKTLSMENIQ
     SLNAAYATSG PMYLSDHENV GSETPKSTMT LGRSGGRLPY GVRMTAMGSS PNIASSGVAS
     DTIAFGEHHL PPVSMASTVP HSLRQARDNT IMDLQTQLKE VLRENDLLRK DVEVKESKLS
     SSMNSIKTFW SPELKKERAL RKDEASKITI WKEQYRVVQE ENQHMQMTIQ ALQDELRIQR
     DLNQLFQQDS NSRTGEPCVT ELTEENFQRL HTEHERQAKE LFLLRKTLEE MELRIETQKQ
     TLNARDESIK KLLEMLQSKG LSAKATEEDH ERTRRLAEAE MHVHHLESLL EQKEKENALL
     REEMHRRFEN APDSAKTKAL QTVIEMKDSK ISSMERGLRD LEEEIQMLKS NGALSTEERE
     EEMKQMEVYR SHSKFMKNKV EQLKEELNSK EAQGEELKKR AAALQAEIGQ VKQELSRKDT
     ELLALQTKLE TLTNQFSDSK QHIEVLKESL TAKEQRAAIL QTEVDALRLR LEEKETMLNK
     KTKQIQDMAE EKGTQAGEIH DLKDMLDVKE RKVNVLQKKI ENLQEQLRDK EKQMSSLKER
     VKSLQADTTN TDTALTTLEE ALAEKERTIE RLKDQRDRDE REKQEEIDNY KKDLKDLKEK
     VSLLQGDLSE KEASLLDLKE HASSLASAGL KKDSRLKTLE IALEQKKEEC LKMDSQLKKA
     HEAALEARAS PEMSDRIQQL EREIARYKDD SSKAQAEVDR LLEILKEVEN EKNDKDKKIA
     ELESLTSRQV KDQNKKVANL KHKEQVEKKK SAQMLEEARR REDTLSDSSQ QLQDSLRKKD
     DRIEELEEAL RESVQITAER EMVLAQEESA RTSAEKQVEE LLMAMEKVKQ ELESMKAKLS
     CTQQSLAEKE THLTNLRAER RKHLEEVLEM KQEALLAAIS EKDANIALLE LSSSKKKTQE
     EVAALKREKD RLVQQLKQQT QNRMKLMADN YEDDHFRSSH SSQTNHKPSP DQIIQPLLEL
     DQNRSKLKLY IGHLTALCHD RDPLILQGLT PPASYNLDDD QAAWENELQK MTQEQLQNEL
     EKGERDNSEL QEFANAVLQQ IADRCPDILE QVVSALEESS
//