ID A0A2Y9NI81_DELLE Unreviewed; 578 AA.
AC A0A2Y9NI81;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Polycomb protein SCMH1 isoform X5 {ECO:0000313|RefSeq:XP_022431127.1, ECO:0000313|RefSeq:XP_022431128.1};
GN Name=SCMH1 {ECO:0000313|RefSeq:XP_022431127.1,
GN ECO:0000313|RefSeq:XP_022431128.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022431127.1};
RN [1] {ECO:0000313|RefSeq:XP_022431127.1, ECO:0000313|RefSeq:XP_022431128.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022431127.1,
RC ECO:0000313|RefSeq:XP_022431128.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR RefSeq; XP_022431127.1; XM_022575419.1.
DR RefSeq; XP_022431128.1; XM_022575420.1.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20108; MBT_SCMH1_rpt2; 1.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047280; MBT_SCMH1_rpt2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF68; POLYCOMB PROTEIN SCMH1; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT REPEAT 1..65
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 73..174
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 511..576
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 172..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 578 AA; 63873 MW; 1A4068ED08F48FFD CRC64;
MKLEAQDPRN TTSTCIATVV GLTGARLRLR LDGSDNKNDF WRLVDSAEIQ PIGNCEKNGG
MLQPPLGFRL NASSWPMFLL KTLNGAEMAP IRIFHKEPPS PSHNFFKMGM KLEAVDRKNP
HFICPATIGE VRGSEVLVTF DGWRGAFDYW CRFDSRDIFP VGWCSLTGDN LQPPGTKVVI
PKNPYPASEA NTEKPSIHSN TKTALEPQPG QRGRKPGKKR GRTPKPLIPH PISTPSKSAE
PLKFPKKRGP KPGSKRKPRT LLNPPPTSPT TSTPEPDTST VPQDAATIPS SAMQAPTVCI
YLNKNGSTGP HLDKKKVQQL PDHFGPAQAS VVLQQAVQAC IDCAYHQKTV FGFLKQGHGG
AVISAVFDRE QHTLNLPAVN SITYVLRFLE KLCHNLRSDN LFGNQPFTQT HLSLTTTEYS
HSHDRYLPGE TFALGNSLGR SLEPHSDSMD STLNPTNLVS TSQNLRNPGY RPLLPSCGLP
LSTASAVRRF CSRGSDRRDA SRQSGRDPSS WTVEDVMQFV READPQLGPH ADLFRKHEID
GKALLLLRSD TMMKYMGLKL GPALKLCYHI DRLKQGKF
//
