ID A0A2Y9NJ83_DELLE Unreviewed; 527 AA.
AC A0A2Y9NJ83;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Cyclin-L1 {ECO:0000256|ARBA:ARBA00019921};
GN Name=CCNL1 {ECO:0000313|RefSeq:XP_022429348.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022429348.1};
RN [1] {ECO:0000313|RefSeq:XP_022429348.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022429348.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin L subfamily.
CC {ECO:0000256|ARBA:ARBA00010589}.
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DR RefSeq; XP_022429348.1; XM_022573640.1.
DR AlphaFoldDB; A0A2Y9NJ83; -.
DR STRING; 9749.A0A2Y9NJ83; -.
DR Ensembl; ENSDLET00000016882; ENSDLEP00000015274; ENSDLEG00000011260.
DR KEGG; dle:111174652; -.
DR InParanoid; A0A2Y9NJ83; -.
DR OrthoDB; 4848076at2759; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IEA:Ensembl.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0043484; P:regulation of RNA splicing; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20592; CYCLIN_CCNL1_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR PANTHER; PTHR10026:SF64; CYCLIN-L1; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF036580; Cyclin_L; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 89..191
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 200..315
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01332"
FT DOMAIN 204..288
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..417
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..449
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..476
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 506..527
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 527 AA; 59713 MW; 4913F661F4CDED03 CRC64;
MASGPHPTAT AAAAAVSSAA PSAGGSSSGT TTTTTTTTGG ILIGDRLYSE VSLTIDHSLI
PEERLSPTPS MQDGLDLPSE TDLRILGCEL IQAAGILLRL PQVAMATGQV LFHRFFYSKS
FVKHSFEIVA MACINLASKI EEAPRRIRDV INVFHHLRQL RGKRTPSPLI LDQNYINTKN
QVIKAERRVL KELGFCVHVK HPHKIIVMYL QVLECERNQT LVQTAWNYMN DSLRTNVFVR
FQPETIACAC IYLAARALQI PLPTRPHWFL LFGTTEEDIQ EICIETLRLY TRKKPNYELL
EKEVEKRKVA LQEAKLKAKG LNPDGTPALS TLGGFSPASK PSSPREVKAE EKSPISVNVK
TVKKEPEDRQ QASKSPYNGV RKDSKRSRNS RSASRSRSRT RSRSRSHTPR RHYNNRRSRS
GTYSSRSRSR SRSHSESPRR HHNHGSPHLK AKHTRDDLKS SNRHGHKRKK SRSRSQSKSR
DHSDAVKKHR HERGHHRDRR ERSRSFERSH KGKHHGGSRS GHGRHRR
//
