ID A0A2Y9NK38_DELLE Unreviewed; 846 AA.
AC A0A2Y9NK38;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=GTPase-activating Rap/Ran-GAP domain-like protein 3 isoform X6 {ECO:0000313|RefSeq:XP_022434404.1, ECO:0000313|RefSeq:XP_022434405.1};
GN Name=GARNL3 {ECO:0000313|RefSeq:XP_022434404.1,
GN ECO:0000313|RefSeq:XP_022434405.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022434405.1};
RN [1] {ECO:0000313|RefSeq:XP_022434404.1, ECO:0000313|RefSeq:XP_022434405.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022434404.1,
RC ECO:0000313|RefSeq:XP_022434405.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022434404.1; XM_022578696.2.
DR RefSeq; XP_022434405.1; XM_022578697.2.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 22..238
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 320..631
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 643..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 846 AA; 93940 MW; 91FB0ABB64CA2477 CRC64;
MNLDKFEKGP REIFHPEIQK DLLVLEEQEG SVNFKFGVLF AKDGQLTDDD MFSNEIGSDA
FQKFLNLLGD TVTLKGWTGY RGGLDTKNDT TGIHSVYTIY QGHEIMFHVS TMLPYSKENK
QQVERKRHIG NDIVTIVFQE GEEPSPAFKP SMIRSHFTHI FALVRYDQQK DNYRLKIFSE
ESVPLFGPPL PSPPVFTDHQ EFRDFLLVKL INGEKATLET PTFAQKRRRT LDMLIRSLYQ
DLMPDLHKNM LNRRSFSDVL PESPKSARKK EEARQAEFVR IGQALKLKSI VRGDAPSSLV
AAGICKKEPW EPQCFCSNFP HEAVCADPWG QALLVSTDAG VLLVDDDLPS VPVFDKTLPV
KQMHVLEALD LLIFRADKGK DARLFVFRLS AVQRGIEGKQ AVKGKYDCRE NKLEKTKGCH
LYAMNTHHSR ELRIVVAIRN KLLLVMRKHS KPSGVTGMSL LSPLPESPVE EFQYIREICL
SDSPSVMTLV DGPSEESDNL ICVAYRHQFD VVNESTGEAF RLHHVEANRV NLVAAIDVYE
DGEAGLLLCY NYSCIYKKVC PFNGGSFLVQ PSASDFQFCW NQAPCAIVCA FPYLLAFTTD
SMEIRLVVNG NLVHTAVVPQ LQLVASRSDI YFTATASVNE VSSGGSSKGA SAHNSPQTPP
GRDTPVFPSS LGEGEIQSKN LYKIPLRNLV GRSIERPLKS PLVSKVITPP TSIGIGIAAI
PVTHSLSLSR MEIKEIASRT RRELLGLSDE GGPRAEGAPK PKSKARKRVE ENQGGPKPGT
VRSTSSERIT SSSLESPSTS EANPEGRYQS TSSDPDPVAE REGSPVWGSS PFQLTASSDE
DIIDLK
//
