ID A0A2Y9NR11_DELLE Unreviewed; 1014 AA.
AC A0A2Y9NR11;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=SAFB-like transcription modulator isoform X5 {ECO:0000313|RefSeq:XP_022435331.1};
GN Name=SLTM {ECO:0000313|RefSeq:XP_022435331.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022435331.1};
RN [1] {ECO:0000313|RefSeq:XP_022435331.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022435331.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_022435331.1; XM_022579623.2.
DR AlphaFoldDB; A0A2Y9NR11; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12678; RRM_SLTM; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR15683:SF5; SAFB-LIKE TRANSCRIPTION MODULATOR; 1.
DR PANTHER; PTHR15683; SCAFFOLD ATTACHMENT FACTOR B-RELATED; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 22..56
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 391..469
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 57..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..204
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..853
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..889
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..946
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 972..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 115107 MW; EA8BB8FF9DD41B3B CRC64;
MAAVTGAVAA SAASGQAECK KITDLRVIDL KSELKRRNLD ITGVKTVLVS RLKQAIEEEG
GDPDNIELTV STDTPNKKPT KGKAHFPSFA GKKQEADELS GDASVEDDAF VKDCELEHQE
AHEQDGNDEL KDSEEFGENE EENVHSKELL SAEENKRAHE LIEAEAIEDI EKEDIESQEI
EAQEGEDDTF LTAQDGEEEE NEKDIAGSGD GTQEVSKPLP SEGNLAEADH TAHEEMEANT
TVKEAEDDNI SVTIQAEDAI TLDFDGDDLL ETGKNVKITD SEASKPKDGQ DVIAQSPEKE
SKDYEMNANH KDGKKEDCVK GDPVEKEARE SSKKAESGDK EKDTLKKGPS STGASGQAKS
SSKESKDSKT SSKDDKGSTS STSGSSGSST KNIWVSGLSS NTKAADLKNL FGKYGKVLSA
KVVTNARSPG AKCYGIVTMS SSTEVSRCIA HLHRTELHGQ LISVEKVKGD PSKKELKKEN
DEKSSSRSSG DKKNMSDRSS KTQASVKKEE KRSSEKPEKK ESKDTKKIEG SKSPGHMVIL
DQTKGDHCRP SRRGRYEKIH GRSKEKERAS LDKKRDKDYR RKDILPFEKM KEQRLREHLV
RFERLRRAME LRRRREIAER ERRERERIRI IREREERERL QRERERLEIE RQKLERERME
RERLERERIR IEQERRKEAE RIAREREELR RQQQQLRYEQ EKRNSLKRPR DVDHRRDDPY
WSENKKLSLD TDARFGHGSD YSRQQNRFND FDHRERGRFP ESSSIQSSSF ERRERFVGHS
EGKKTRPSAR REDPGFERYP KNFSDSRRNE PLPPRNELRE TDRREVRGER DERRTVIIHD
RPDITHPRHP REGGPNPSRP TSWKSEGGMS TDKREARVER PERSGREVSG HSVRGAPPGN
RSNASGYGNR EGDRGVITDR GSGAQHYPEE RHVVDRHGRD TSGPRKEWHG PPSQGPSYHD
ARRMGDGRTG AGMITQHTSN ASPINRIVQI SGNSMPRGSG SGFKPFKGGP PRRF
//
