ID A0A2Y9NVJ3_DELLE Unreviewed; 602 AA.
AC A0A2Y9NVJ3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X2 {ECO:0000313|RefSeq:XP_022433538.1};
GN Name=ARNTL2 {ECO:0000313|RefSeq:XP_022433538.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022433538.1};
RN [1] {ECO:0000313|RefSeq:XP_022433538.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022433538.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022433538.1; XM_022577830.1.
DR AlphaFoldDB; A0A2Y9NVJ3; -.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11469; bHLH-PAS_ARNTL2_PASD9; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF48; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Receptor {ECO:0000313|RefSeq:XP_022433538.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483}.
FT DOMAIN 73..126
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 144..209
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 344..393
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 33..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 602 AA; 67085 MW; 6E1BF500EE9F116B CRC64;
MATEEEEAAR GKVLIEGNQC IAAMVSSHLS PWTKPATIGS FSPHVTEFPR KRKGSDSDPS
QMEDGEQQVK MKSFREAHSQ TEKRRRDKMN NLIEKLSAMI PQCNPMARKL DKLTVLRMAV
EHLRSLKGMT SSYAGNNYRP SFIQDNELRH LILKTAEGFL FVVGCERGKI LFISKSVSKI
LNYDQASLTG QSLFDFLHPK DVAEVKEQLS SSDISPREKL IDAETGLQAH GNFHTGRSCV
YSGSRRSFFC RIKSCKISVK EEHECLLNSK KKDHRKFCTI HCTGYLRNWP PNIVGMEEET
DNKKDSSNFT CLVAIGRLHP YIVPQNSGEI KVKPTEFITR FAVNGQFVYV DQRATAILGY
LPQELLGTSC YEYFHQDDHS NLTDKHKAVL QSKEKIFTDS YKFRAKDGSF VTLKSQWFSF
TNPWTKELEY IVSVNTLVLG HSDTGETSLL PCSSQSSEGS SRQSCISVPG MSTGTVLGAG
SIGTDIASEL LDLQRLQSSS SLDDSSPTDL LKDTHTINCR NMSNKELTTL SPSEIGELQA
TKQNQSAVAP HRHEPLLGEG AQLDFDALCD NDDTAMAAFM NYLEAEGGLG DPGDFSDIHW
AL
//
