ID A0A2Y9P6U5_DELLE Unreviewed; 632 AA.
AC A0A2Y9P6U5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zinc finger protein 90 homolog isoform X2 {ECO:0000313|RefSeq:XP_022439077.1, ECO:0000313|RefSeq:XP_022439078.1};
GN Name=ZFP90 {ECO:0000313|RefSeq:XP_022439077.1,
GN ECO:0000313|RefSeq:XP_022439078.1, ECO:0000313|RefSeq:XP_022439079.1,
GN ECO:0000313|RefSeq:XP_030616944.1};
OS Delphinapterus leucas (Beluga whale).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Delphinapterus.
OX NCBI_TaxID=9749 {ECO:0000313|Proteomes:UP000248483, ECO:0000313|RefSeq:XP_022439077.1};
RN [1] {ECO:0000313|RefSeq:XP_022439077.1, ECO:0000313|RefSeq:XP_022439078.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022439077.1,
RC ECO:0000313|RefSeq:XP_022439078.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022439077.1; XM_022583369.1.
DR RefSeq; XP_022439078.1; XM_022583370.1.
DR RefSeq; XP_022439079.1; XM_022583371.1.
DR RefSeq; XP_030616944.1; XM_030761084.1.
DR Proteomes; UP000248483; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23234:SF10; GENE 10130-RELATED; 1.
DR PANTHER; PTHR23234; ZNF44 PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 12.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248483};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..85
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 208..235
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 251..278
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 279..306
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 307..334
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 335..362
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 363..390
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 391..418
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 446..473
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 493..520
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 521..548
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 549..576
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 577..604
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 605..632
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 90..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 72394 MW; 28BC020D32118136 CRC64;
MAPRPPTARP QESVTFKDVA VNFTQEEWHH MDPAQRRLYR DVMLENYSHL VSLGYQVSKP
EVIFKLEQGE EPWIAEGEIQ RPFCPDWRTR PEAKSSNQQS ISEVSLSTDD PSCATLEDTW
DVNGQLERHK ENWKRHLGPD ASTQKKIVTP EEACEQNKFV ENSRLNTDLV TQLNIPPRSN
ECDTLGSNLG HNSDLLSQNN ILAKKKPYKC NKCRKAFIHR SSLTKHEKTH KGDGTFPNGT
DQGIYPGKKH HECTDCGKTF LWKTQLTEHQ RIHTGEKPFE CNVCGKAFRH SSSLGQHENA
HTGEKPYQCS LCGKAFQRSS SLVQHQRIHT GEKPYRCNLC GRSFRHGTSL TQHEVTHSGE
KPFQCKECGK AFSRCSSLVQ HERTHTGEKP FECSICGRAF GQSPSLYKHM RIHKRGKPYQ
SSNYSIDFKS SSLTQDENTL TEVKSYHCND CGEDFSHITD FSDHQRIHTG ENPYDCEQAF
SQQSISHPGE KPYQCNVCGK AFKRSTSFIE HHRIHTGEKP YECNECGEAF SRRSSLTQHE
RTHTGEKPYE CIDCGKAFSQ SSSLIQHERT HTGEKPYECN ECGRAFRKKT NLHDHQRIHT
GEKPYACKEC GKNFSRSSAL TKHQRIHTRN KL
//
